Hi, I'm a newbie. I just wanted to share that I've been on Wellbutrin for 1 year. Wellutrin alone does not work well for my depression and it gives me anxiety, plus insomnia. My doctor added Lexapro to take with Wellbutrin and it seemed to even me out but did nothing really for the depression. After trying this combo for about 9 months, I requested a change since it wasn't helping. Now I take Zoloft with Wellbutrin and I feel great!! I think this is my magic bullet!! I am very sensitive to drugs so I only take 50mg of Wellbutrin and 25 mg of Zoloft (both generic). I take them together in the morning and no side effects so far. I have energy, my mood is great, no anxiety, and I can focus at work. So far, so good! It has only been one week with this new combo and it may be too soon to tell how it will help me in the long run, but I wanted to share my experience thus far.
Has anyone else had good success with this combination??
I'm so happy to hear you have found a combo that works for you! I've been on zoloft for two years ago but it wasn't working enough so my dr added Wellbutrin but it didn't help and made me shaky. I'm now just on the zoloft again. Waiting to see my psychiatrist to see what to do next cause zoloft isn't cutting it for me. It's great when you find a combo that works, best of luck! :)
21 Nov 2014
I was thrilled when I read this post by you. I too am very sensitive to meds and I am trying to find the magic bullet. Not only that, but I am currently taking half of a 50 mg Zoloft and cutting a 75 mg Wellbutrin in 2/3 a day. Is this still working for you? I have anxiety and depression. Wellbutrin alone makes me have panic attacks and Zoloft alone makes me tired. Would love to hear from you!
6 Dec 2014
Thats great! Ive found a good combo with Zoloft and Wellbutrin myself. I take 100 mg of zoloft a day and 300 of the wellbutrin a day. It works great for me!
19 Feb 2015
I am also a newbie to meds but no stranger to depression... My psychiatrist started me on Zoloft 100mg and it was good for a minute then I just platoed. I went back to him and we bumped it up to 150mg and that almost seemed like it made things worse... My last visit with him was extremely successful, I was bumped up to 200mg of Zoloft and 150mg of wellbutrin.. This has been my MIRACLE! I have never felt better! I had really bad side effects starting out with wellbutrin but it is literally the other side of the hill, I haven't been this happy in 8 years! I will say though that I have noticed a loss of appetite and a little weight loss, which for me is probably a good thing:) anyway this is a great combination for me!
13 Jun 2015
I have been trying every med known for major depression and anxiety. I'm now on Zoloft and doc was thinking of adding Wellbutrin next week. I've been majorly depressed for a year now and nothing is working. Please help with words of encouragement. I feel like nothing is gonna work. I've tried Effexor, Prozac, remeron, celexa and now Zoloft.
16 Jul 2015
Hi. I'm back. No more Zoloft for me. I'm still on the Wellbutrin but this time with Prozac. It's a great combo for energy & motivation! The downside is insomnia :( I can't go into a deep sleep without a sleeping pill. I didn't want to add more pills to my regime, but unless I find an SSRI that will help me sleep I'm stuck with this combo of pills. I have a doctor appointment tomorrow. I will let you all know if we go a different route.
16 Jul 2015
I haven't started the Wellbutrin yet nervous that'll it will spike my already bad anxiety. I am scared that my depression won't ever go away. It's been a year of mes trials.
5 Aug 2015
Has anyone else taken a year to find the right meds? I'm on 200mg of Zoloft and 150mg og seroquel
30 Nov 2015
Hi everyone. I am newbie as well. I've been on Zoloft a few years at 75 mg, and now 50 mg... my dr added Wellbutrin for smoking cessation but said I may end up liking the combo together and don't have to stop taking Wellbutrin after I quit smoking. I am really worried about the seizure risk. Mainly because I am still partying a lot and drinking... I am still kind of holding onto the youth I have left, and I know I know the easy solution is "just dont drink" but I want to know about what the risk level actually is... anyone have any idea? I am taking 150 mg of Wellbutrin, just started yesterday so I have 2 doses in me. Not too bad so far but it's obviously early. I am supposed to up the Wellbutrin next week to 400 mg daily but I don't want to as I know the risk of seizure goes up from there. So I may not do it.
16 Dec 2015
I'm currently taking 200 MG Zoloft and 300 MG Wellbutrin XL. Neither one alone helped with my depression. I had anxiety and insomnia prior to being on these meds so those aren't anything new to me. I've tried pretty much every antidepressant there has been on the market for the past 20 years. And this seems to be the only combination that has ever worked for me. There are some negative side effects, however there are more positive side effects and those greatly outweigh the negative, so I just stick with it.
2 May 2016
I'm on wk 5 Zoloft 100 mg... still upset tummy but trying to ride it out few more weeks hoping not to change again... his next suggestion is paxil. Ive already done cymbalta, effector, lexapro. I asked MD today about adding wellbuterin to address the chronic fatigue but he reluctant to add on. Is that normal practice to keep trialing one drug after another? I keep reading people success with dual meds. Please advise.
18 May 2016
I have tried Wellbutrin (aka Zyban) and what that did to me was a night in the hospital crisis unit. That drug made me hit rock bottom and my family doctor sent me straight to the hospital. I turned violent and suicidal from that drug and is not for me. My Psychiatrist has tried without success Prozac and about 10 others before hitting my drug of best success so far. I now take 200 mg Sertraline hydrochloride (Zoloft) with dinner plus 1 mg Clonazepam in the morning and in the evening and so far so good - its been about 3 weeks now and I now feel about 5 out 10 on a scale of 10 I have been around 3 and as low as1 at times. Depression and anxiety combined is very scary and I have been dealing with it for along time.
4 Jun 2016
Wellbutrin has been added to my combo recently and at the moment I'm very optimistic of what to expect. I'm currently taking 150 mg Zoloft, 150 mg Wellbutrin and 15 mg of Buspar 4 times a day. I've been on Zoloft off and on for 12 years and although it worked great for me at first, it has not had the same effect over time. Zoloft has had crazy side effects for me these past few years (I'm now 25) and my psychiatrist looks at me like I have no idea what I'm talking about when I ask if maybe I should switch. My feelings of sadness, hopelessness, and crying spells stopped, but I still had zero motivation or energy. My social anxiety was through the roof, I was hardly able to go to work, and I started having anxiety attacks while driving or in crowded/noisy places. Buspar has changed my life as far as my anxiety is concerned.
I couldn't even recognize how bad it was up until it started to get better, my obsessive thoughts and internal negative dialogue eased up tremendously. It's not like other anti anxiety medicine, I don't feel groggy or less able to function. I've just started the Wellbutrin in hopes to raise my energy and motivation, I've felt more motivated the past few days, but I'm waiting to see if that is maybe just a placebo effect :P With any medication, especially psych meds, it can take a few weeks before you start to feel the change, so if you've just started hang in there! But, like always, if you have any serious side effects that started shortly after starting, you should talk to your doc ASAP!!
22 Jun 2016
You have to eat with the Wellbutrin or it will cause shakiness. Zoloft & Wellbutrin has been a great combo for me, helps my depression & energy levels tremendously... I feel like I am enjoying day to day life again!
30 Aug 2016
I'm thrilled to hear of your relief! I've been on Zoloft for 18 years. It's helped tremdously with my panic disorder. The lack of motivation and fatigue from Zoloft can be debilitating. I took a year off and my energy and drive came back... So did my panic! I'm back on Zoloft and my Dr. just prescribed 150xl. Wellbutrin. I don't like the idea of more medication, but I don't want to feel like a zombie. I've been on it 2 days, feel jittery. How long before anyone felt the positive results and how long did any side effects last? Thanks in advance!!!
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