I have heard sertraline can have a negative affect on being able to orgasm, is this true or does it depend on the person?
Every medication as you mention affects each individual differently, side effects, interactions, benefits,etc.
With regards to your question, a possible common side effect of Zoloft (sertraline) is :
decreased sex drive, impotence, or difficulty having an orgasm.
All the best,
Yes, it's a common side effect.
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