Can you take tramadol and Flexeril at the same time?

Interactions between your selected drugs
Major
cyclobenzaprine tramadol
Applies to: Flexeril (cyclobenzaprine), tramadol
TraMADol may rarely cause seizures, and combining it with other medications that can also cause seizures such as cyclobenzaprine may increase that risk. The interaction may be more likely if you are elderly, undergoing alcohol or drug withdrawal, have a history of seizures, or have a condition affecting the central nervous system such as a brain tumor or head trauma. Talk to your doctor if you have any questions or concerns. Your doctor may be able to prescribe alternatives that do not interact, or you may need a dose adjustment or more frequent monitoring by your doctor to safely use both medications. You should avoid or limit the use of alcohol while being treated with these medications. Also avoid driving or operating hazardous machinery until you know how the medications affect you. It is important to tell your doctor about all other medications you use, including vitamins and herbs. Do not stop using any medications without first talking to your doctor.
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Other drugs and diseases that your selected drugs interact with
tramadol interacts with more than 300 other drugs and 8 diseases.
Flexeril (cyclobenzaprine) interacts with more than 300 other drugs and 2 diseases.
Interactions between your selected drugs and food
Moderate
cyclobenzaprine food
Applies to: Flexeril (cyclobenzaprine)
Alcohol can increase the nervous system side effects of cyclobenzaprine such as dizziness, drowsiness, and difficulty concentrating. Some people may also experience impairment in thinking and judgment. You should avoid or limit the use of alcohol while being treated with cyclobenzaprine. Do not use more than the recommended dose of cyclobenzaprine, and avoid activities requiring mental alertness such as driving or operating hazardous machinery until you know how the medication affects you. Talk to your doctor or pharmacist if you have any questions or concerns.
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Moderate
tramadol food
Applies to: tramadol
Alcohol can increase the nervous system side effects of traMADol such as dizziness, drowsiness, and difficulty concentrating. Some people may also experience impairment in thinking and judgment. You should avoid or limit the use of alcohol while being treated with traMADol. Do not use more than the recommended dose of traMADol, and avoid activities requiring mental alertness such as driving or operating hazardous machinery until you know how the medication affects you. Talk to your doctor or pharmacist if you have any questions or concerns.
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Therapeutic duplication warnings
No therapeutic duplications were found for your selected drugs.

https://www.drugs.com/interactions-check.php?drug_list=2221-0,758-386

regards...

NO, you can't take them together.