I have been on antidepressants for 10 years and found that zoloft had giving me relief, but after the birth of my child and my husband getting cancer i have not been able to be the same. my dr switched me effexor and my depression lifted but i was not myself, i still stuck it out for 3 years, now the effexor stopped working, i went to prysitc MADE ME WORSE, so now im back on zoloft... i know it worked before so it should work again, but its like a horrible waiting game. I keep reminding myself that I have alot to be greatful for, my son, my husband, who has fully recovered, a great job etc.. but i still cant find normal... I want to enjoy my life, im on my fourth week on zoloft