In the package insert, male infertility is indicated as a possible side effect of the drug. On the other hand, it is known as an anti-oxidant, which may be beneficial for fertility. Thus, should allopurinol be avoided by men who have low sperm quality or the other way round?
Why allopurinol would cause male infertility?
Question posted by DereviaS on 4 Aug 2010
Last updated on 8 August 2010
What's the possible mechanism of this side effect?
Allopurinol (Zyloprim) is a prescription medication approved for preventing:
High uric acid levels due to cancer treatment
Prevent elevation of blood uric acid in patients undergoing chemotherapy for the treatment of certain cancers and in patients with recurrent calcium kidney stones.
This drug is not used to treat male infertility.-It is a drug used primarily to treat hyperuricemia (excess uric acid in blood plasma) and its complications, including chronic gout.
Off-Label Allopurinol Uses
Mouth sores due to chemotherapy (used in a mouthwash form)
Prostatitis (inflammation of the prostate gland)
Leishmaniasis (a parasitic infection)
- Allopurinol uses and safety info
- Allopurinol information for Healthcare Professionals (includes dosage details)
- Side effects of Allopurinol (detailed)
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