i have been on morphine sulfate ER 60mg. for 5 years my drug store gave me morphine sulfate CR 60mg. this time.I have never taken the CR before and i'm itching all over my face and have a rash
What is the difference of morphine sulfate ER and morphine sulfate CR?
Question posted by EMDEV50 on 21 Sep 2010
Last updated on 16 May 2013
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4 Answers
pbp4YHWH
1 Nov 2012
O.K. What if the scrip says: "Morphine Sulfate CR Tablet Extended Release 12 Hour 100 mg Orally"; if the active ingredients are supposedly the exact same in both, yet - the IN-active ingredients supposedly differ with both, how is it then even possible to fill such an Rx order with "CR & Extended Release" on a single drug Rx ? Also, if it is true that CR vs. ER differ ONLY in the INACTIVE ingredients, what are the inactive ingredients true differences with both - and then - why are people reporting allergic reactions to the 'inactive' stuff ? What are the exact differing ingredients between CR & ER ? We need a Tech or Lic. Pharmacologist to truly answer this one. Prev.answrs R way 2 vague thus far! T.Y.V.M. pbp4YHWH.
heathermd577
16 May 2013
@pbp4YHWH It is not that there is a difference between the inactive ingredients, it is about the way the manufacturer labels it. The difference can actually be the ACTIVE ingredients. The FDA only requires generic medications to have an amount of the active ingredient to be within 20% of the original name brand. That 20% can be less or more, so if they changed the brand, the OP may have been taking a brand that has 20% less of the active ingredient and then the new ones have 20% more. That would mean that the increase in medication is 40%, so taking the regular dosage is like taking a dose and a half every time. Calling it CR or ER is just what the company that made the generic decided to call it, just like Robitussin and Waltussin, they are both the same medication with only a change in the name to represent the difference in the two companies that made it.
HARDTOOLUV
13 June 2012
For those who dont know cr means continuse release an er is extend release! Trust me I know I have been on both for over 10 years!
sunnisheryl
11 Oct 2011
the ER and CR are different due to the inactive ingredients. I have taken Soma's for years. I always got the Dan brand. Last month my pharmacy changed to a brand that had a V on 1 side. I broke out in hives, had red welts all over my body, and it itched and burned so bad I was crying. It's due to the different buffers they put in their medicines. One is ER and has certain inactive ingredients, the other is CR and it is different or it would have been named ER. Look up each drug and check what exactly is in each pill. Then you should see the difference. Look at the inactive ingredients. It's one of them that your allergic to. The amounts of each inactive ingredients are different, as well as what inactive ingredients they put in each. Be sure to tell your pharmacist that you are allergic to the CR brand! If they don't have ER, take your prescription somewhere else, where they do.
Not only is an allergic reaction uncomfortable (unbearable on my part), it is very dangerous! In some cases people have died from allergic reactions. So DON'T LET ANYONE TELL YOU THEY ARE THE SAME, CAUSE THEY ARE NOT. IF THEY WERE THEY WOULD HAVE THE SAME NAME.
shannabanana71
1 Dec 2011
I am on Morphine sulfate 30mg cr 1 per 12 hours. 2 a day. the first week I felt "high" and broke out in hives. I called my dr and they (spinal clinic) advised me to "wait it out" as I have had worse reactions: ARGH! But , I took myself OFF the morning pill and only take the night one and it seems to be lessening, the reactions that is. This may or may not be helpful? I dont know.
Inactive
21 Sep 2010
ER stands for extended release and CR stands for controlled release it does the same exact thing no difference your pharmacy probably ran out of the ER tabs.
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Further information
- Morphine uses and safety info
- Morphine prescribing info & package insert (for Health Professionals)
- Side effects of Morphine (detailed)
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