I've been on 450 mg for several years. I have had alot of agitation and am short tempered. I don't know if its me or the medicine to be honest. Otherwise this medication really saved my life. Depression got me to the point I couldn't function and my life is just fine in that department due to Wellbutrin. Anyone else have anger issues / agitataion?
Wellbutrin and agitation/anger outbursts? Anyone else?
- 28 Jul 2010 by VeniceGal
- 12 April 2021
Uh, yeah. lol. I thought that was just me having a moodswing. haha. I'm diagnosed with being bipolar II and for the most part I am pretty even with my moods, especially in the spring/summer months. I am on 450mg of Wellbutrin XL and 400mg of Topamax. I used to be on Lamictal and Geodon a few years ago to help with mood stabilization, but I had ECT (electro-convulsive therapy) because my depression was so difficult to treat with meds and the Dr. was looking for a way to reduce or eliminate some or all of my meds. Well, it started out as me only being on 150mg of Wellbutrin XL and 50mg of Topamax and they took me off my other 2 meds..and over the past 2 1/2 years I have went all the way back up to my max dose of Topamax and Wellbutrin and I still get depressed pretty bad occasionally and when I get agitated my fiance' says I'm pretty mean about things..like not just a little crabby.
Recently I also had to get some Klonopin for anxiety (as needed) because that part of the bipolar disorder has been starting to act up again too. I know this may no be EXACTLY like what you have gone through, but I AM on 450 mg of Wellbutrin XL, and I AM suffering from a form of depression.
Hi Venice Gal, Wellbutrin can cause aggitation and panic attacks!!
An excellent shrink once told me that Wellbutrin is the worst anti-D for anyone who has anxiety problems, and 'tis true... from personal experience.
Talk with your doc about the aggitation you feel, perhaps an anti-D that has a calming effect might be a better option.
Wishing you the best,
YES! I've had MANY more angry outbursts and they have been more extreme and quick. Hard to stop once they start. Interesting comments about anxiety. Also applies here. While there are unpleasant side effects that Wellbutrin doesn't have, this anger and quick/short temper is quite problematic in family life.
Oh wow! So glad I am not the only one.
I suffer from severe anxiety. One day I started shaking and it didn't stop for a year. I was on Paxil for a while but my libido went to zero so my doc switched me to Wellbutrin. Libido back to normal but I kept having these extreme anger outbursts. The smallest things will set me off and I seriously want to break stuff.
I guess I'll have to continue to walk away from those situations but I am glad to learn that it's from the drug.
I've been on Wellbutrin 300 mg and Pristiq 100 mg for a while. My doctor recently upped the Wellbutrin to 450 mg. The first day I took the higher dose I was in heaven. I felt good, music sounded great, and I was enjoying myself in general. Day two and three and began to become easily angered and upset. I also notice some sexual issues. I went back to 300 mg the next day. The anger issue got better. I've been meaning to speak to my doctor about this because I refuse to put my love ones through my crazy mood swings. However, I wonder if this anger would eventually subside and I can go back to heaven.
I am so happy I sought this information out! I've been diagnosed with MDD/GAD/PTSD & I have been on a number of antidepressants over the last 20+yrs. Sometimes they just stop working so we make the change. Recently I was on Cymbalta for many, many years but gained a TON of weight, had no sex drive and felt as though the med wasn't doing what it needed to do any longer. I was getting more lows than I'd had in years. So, I tapered down over 3wks with doc supervision and made the switch to Wellbutrin. It was the hardest med change i've EVER gone through. I've now been on the Wellbutrin for about 6wks and do notice I have more energy ((most of the time)) which is welcome. However, the ANGER!! Oh my word. The smallest things set me into a complete tailspin that I cannot control. I do not like it at all. I have to admit, I teared up a bit seeing some of the other stories here because I felt like I was reading my own.
I called my doctor today to try to see what her suggestion is going to be and of course she's out of the office till Monday. Initially she had wanted to do a combo therapy of Prozac/Wellbutrin but I declined the Prozac due to the weight gain issues that can come with it (i also have Polycystic Ovarian Syndrome so losing weight is sooooo hard for me). But now I feel like I made a mistake not getting put on the combo.
Does anyone else have any experience with combination meds?
Hello there, My doctor raised my dose about a month and a half ago and I've noticed some real anger outbursts happen along with being easily agitated over little things. I know my temper can get the best of me; however this feels like a raging anger that I normally don't have. The dosage increase absolutely stopped my tobacco cravings and I have been tobacco free for almost two months now so that has been a big blessing. These anger issues though are starting to cause relationship issues, so hopefully we can figure it out!
I have taken generic Wellbutrin SR off and on for several years. I notice that when I go back on it, in the first 2 weeks of being on it, I have to watch my temper. I get a little more edgy than usual at that time. But I can also say that after a week or 2 the agitation and irritability disappear and feel normal again. Wellbutrin gives me energy and motivation. It is the only antidepressant that I have had positive results with, and it lifts my anxiety/depression successfully.
Hi I have only been on Wellbutrin for about a week now but I noticed almost immediately I have been extremely and I mean extremely angry. It seems the littlest unimportant thing is setting me off. I cannot control the anger at all. I am not sure if it is the medicine or not as I feel angry all the time. I am on Wellbutrin for weightloss. I am pretty sure I was on it a few years ago for chronic pain and I don't remember feeling like this.
I think Wellbutrin is the corporate of my wife sudden personality change and irritability. I'm glad to see that this is not all in my head.
I have been on the Wellbutrin for about I have been on the Wellbutrin for approximately four to five months. I was given this medication to additionally help me sleep. I had to run out of my medicine and about 2 Days Later realized it was actually affecting my depression. And the week that I did without my medication to be honest I have never wanted to hurt somebody or myself more in my entire life and I'm not a confrontational or angry person. I got back on my medicine and actually have the dosage increased because it wasn't working like it had been in the beginning. Now I have extremely uncontrollable mood swings. I am either extremely happy or extremely angry and unfortunately my husband usually gets the butt of it. I have never been an angry person like this with such uncontrollable rage and the quickness for violence. I absolutely believe this medication can be a danger to the right person.
I just spoke with my doctor today and they are going to take me off of it because he seems to think it is hurting me a lot more than it's helping me I would definitely suggest you talk to your doctor about what is going on. I hope things get better for you just as I do myself
I was on generic Prozac for several years but it was making me way too lethargic and unambitious, so I asked my doctor to switch me to something that wouldn't make me so tired and lazy. She put me on 300mg Wellbutrin XL (generic) and now I am extremely angry and irritable all the time. (I have been taking it for over a month). I snap at the least little thing and can't seem to control my temper and outbursts. It's like I don't have any control over my emotions. This is very concerning to me as I am not normally a mean or vicious person. What is going on? I fully believe that the Wellbutrin is the cause. I am going to stop taking it immediately and go back on the Prozac. I will find other methods of dealing with my lack of energy. I just started taking a "greens superfood" powder to aid my overall health and I'm hoping that it will ramp up my energy level enough to offset the Prozac. I cannot tolerate the negative side effects/feelings that Wellbutrin gives me... nor the extreme headaches. I hope this helps... best of luck!
I've been on Wellbutrin for over a year. I've been with my boyfriend for 3 and I have a child of my own. My anger issues are pushing him and his son away and I don't blame them. I feel terrible for my son I feel like I am constantly ruining his childhood. Sometimes I feel he'd be better off without me around. I try to control my anger but before I know what's happening I am seeing red and being unbearable to those around me. I usually ruin family vacations. I constantly feel like I am not normal and people should just avoid me for their own good. I'm wondering how much longer my boyfriend will stick around I'm not sure why he hasn't left yet I'm not anything special or worth anything. I'd rather be sleeping than awake. I am glad I'm not the only one with hulk anger problems and that it might be the meds.
When I'm coming down from my anger I have instant regret and feel even more worthless, and tell myself well next time I'll just take a deep breath and walk away. 99% of the time there is no thought process before I flip my lid and everyone is affected. Any helpful tips will be greatly apperciated.
Yes, I am also experiencing anger/agitation. I switched from 20mg lexapro to 150 mg Wellbutrin xl 5 weeks ago and now I am switching back to lexapro but will try 10mg. My only reason for switching was a lack of sex drive on the 20mg of lexapro. For some reason my sex drive was fine on 10mg of lexapro so I am hoping this dose will be ok for me now.
My side effects from switching from 20mg of lexapro to 150 mg of Wellbutrin XL are listed below. BTW I started 10mg lexapro in spring 2013, upped to 20mg in spring 2014 after dealing with a tragedy, gained 10lb weight over it, lost my sex drive but was the happiest I ever felt in my life. If I did not have a boyfriend I would be fine with the 20mg, even with the carb cravings/extra weight. But since I do have a boyfriend I want to want sex again so I decided to switch.
1. dizzy/lightheadedness (lasted first few weeks)
2. night sweats so bad I had to change clothes every night because I was dripping and they were soaked. I had to sleep with a fan on full blast directly on me just to minimize it.
3. Anger/agitation, especially noticeable when I am driving or teaching. I became a stricter teacher and did not tolerate things I had previously been fine with. My poor students! Oh well, it wasn't that bad but definitely noticeable with students who had needed discipline. I was milder and more calm with them while on Lexapro.
4. Repetitive thoughts/anxiety, constantly dwelling on little things and imagining the worst, like the days all of my loved ones will eventually die.
5. Depression, so bad I just want to sleep all day and not do anything. The anger seems to help feed it.
6. Crying over little things and abruptly. One quick news clip is enough to make me cry.
7. Decreased appetite but it feels like I'm just so depressed now and that is why I just don't find joy in it or many other things that I should.
It's hard to tell.
On lexapro I was more level-headed, happier and productive. I read some posts on here from people saying the Wellbutrin SR is better than the XL. I am so fed up with the XL that I am too scared to try the SR.
Well, I just wanted to share my story because I have appreciated reading the comments left by others and figured it was my time to share.
Oh my gosh. I felt so angry when taking well butrin I want to scream at people, little things agitate me and I became physically violent. My psychiatrist claims that making people feel angry is not a side effect of well butrin but look at all the people who claim they experienced that while taking it! Well butrin also increased my appetite and I gained weight when on it. Drug companies claim the opposite. That is BS in my opinion. They just don't want to get sued. They can't claim to know how a drug is going to affect each individual who takes it. I think hormone therapy is the answer to treating depression. Not antidepressants.
- Wellbutrin Information for Consumers
- Wellbutrin Information for Healthcare Professionals (includes dosage details)
- Side Effects of Wellbutrin (detailed)
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