I've been on 450 mg for several years. I have had alot of agitation and am short tempered. I don't know if its me or the medicine to be honest. Otherwise this medication really saved my life. Depression got me to the point I couldn't function and my life is just fine in that department due to Wellbutrin. Anyone else have anger issues / agitataion?
Wellbutrin and agitation/anger outbursts? Anyone else?
Question posted by VeniceGal on 28 July 2010
Last updated on 27 May 2023
40 Answers
I have been taking it for probably over a year. Within the last month I have been angry about everything. I have no idea where it came from until I saw that Wellbutrin is the side effect. I don’t know if I should change my antidepressant or what??
Hi, Selmer!
Side effects generally resolve over days to a few weeks... a year is much too long. You need to have a consultation with your doctor about your treatment plan. A dosage adjustment? A switch to another medication? Also, you'll want to rule out any other underlying cause for your anger.
I am a 63-year-old Caucasian female. I have suffered from PTSD anxiety and depression my entire life.
Like many others my age I was raised in a home with parents who had Experienced the Great depression , World War II , racial unrest and mothers working outside of the home .
Throw in alcoholism and drug addiction .
The hard-working man deserves to drink and there was nothing wrong with mothers little helper that she got from her family doctor .
Or so that was the belief of many at the time.
Unfortunately I was not diagnosed until about 30 years of age .
Prior to that I had been misdiagnosed for many years .
Most of us know it’s just been a little more than 10 years ago that mental illness and addiction were looked upon negatively and needed to be hidden .
Now every small-town paper in America has somebody celebrating their recovery on the front page .
I don’t really know how I feel about that.
Don’t get me wrong I’m happy for everyone that has successful recovery from drugs and alcohol.
But I have never seen a front page story about Mr. Jones got over his kidney stones etc.
Most people now think nothing about saying oh I’m bipolar oh I have PTSD I suffer from anxiety or I’m a recovering alcoholic or addict .
Don’t get me wrong there are still the judgemental .
I have been on a myriad of psych meds to say the least.
I have now been taking Wellbutrin 100 mg twice a day for several years now .
I also take Klonopin 0.5mg daily for anxiety .
I have been noticing what I call anger flashes for about a year now .
The remedy that has worked for me is physical release , running ,walking,
working out .
I even smashed an old keyboard with a hammer (doctor suggestion).
The physical release is wonderful and I found that much of my anger subsided.
I believe that a great number of people are like me , mad at the world for changing and stifling life.
After being newly diagnosed I had some major anger issues .
I feel I went so long without a voice and now I was loaded for bear.
But alas I had good doctors that helped me deal with it and taught me that most mental illnesses are situational and environmental very little is organic .
So having said all that , perhaps some of you had anger issues prior to being successfully treated for depression .
Has it been bottled up in you like it was for me .
Are you in a situation or an environment that is making you ill?
I hope something in this post has helped someone.
I know it helped me just to say it.
Hoping good fortune and health to all. Miss Lucy
"Psychiatric Very common (10% or more of users): Agitation (up to 31.9%) Common (1% to 10% of users): Anxiety, hostility, irritability, mania/hypomania, nervousness" These are common to very common side effects that generally resolve within days to several weeks. If they persist longer than that it should be reported to your health care professional. They are also potentially symptoms of hypomania which can be induced by antidepressants in some people so be sure to alert your doctor/prescriber.
Good afternoon. That's some of the side effects I’m having right now. I’m very mean right now and temper is real short. I get irritated easily and don’t want to be bothered.
Adult male with ADD executive function disorder long term depression problems. Dr tried every version of bupropion(Wellbutrin) to address issues including not sleeping as wellbutrin can make you stay awake if late dose etc. Every time saw much more anger outbursts unlike normal personality. Also caused suicidal thoughts. After taking lower doses, extended release doses, and taking split doses at different times of day from age 20 to 22, finally gave up due to side effects and also was not really helping the ADD or depression. Doing better now on high dose of high-quality fish oil and more exercise but still struggling. After stopping Wellbutrin the anger feelings/outbursts definitely went away and the bad suicidal thoughts. The depression is improved on the fish oil.
YES!! I am pissed off right now and it's my first day on this drug. Lol! I went off of trintellix, which did nothing to wellbutrin and this is only my first day on 150 mg and my attitude is foul and I can tell if I continue I'm going to piss alot of people off and be an unhappy person regardless of any other benefit it may have given me, this is not the drug for me.
Good morning. I started taking Wellbutrin xl starting about two months ago. I started at 150 mg and have gone up to 300 mg to see if it would help take the edge off of my depression. Although I don’t feel as sad or fall into a dark hole like I used to, I have begun to have super fits of rage like never before. The smallest things have been setting me off and in a terrible way. I actually punched through glass and cut my hand. I also broke my computer. This is very frightening to me because I did not feel this way when I was not on Wellbutrin. I admit I had a temper but nothing like this. I recently lashed out at my sister and told her horrible things, things that I would’ve never in a million years told her while I was off this medication. It has actually damaged our relationship a little bit.I feel like Wellbutrin has amplified my temper by 150%. So, I decided to do some research and found all of you guys.
It is very alarming that we all seem to be experiencing the same sorts of side effects with anger. I’m going to drop back down to 150 mg to see how I do. If this does not work then I will have to look at alternative options. This is the first time in my life that I’ve ever taken antidepressant drugs and I hope there is something out there that can help curb my sadness.
I'm on it and yes it makes me feel angry. I get crazy thoughts as well. I'm about to stop to taking it.
I started taking Wellbutrin about a month ago and I have explosive outbursts of anger were I really want to hurt someone. The other night when I was using the restroom at a fast food restaurant someone came in and started kicking the paper towel holder and I yelled at them and told them "I was going to come out there and beat their ass!". Fortunately for them they stopped and left right away. I was SO disappointed because I wanted to beat the holy crap out of them. On Wellbutrin I really really want to hurt someone. And I am NOT like that normally. I have to stop the Wellbutrin immediately. The normal me would never want to hurt anyone. I am so glad I found this site about Wellbutrin.
Thank you. For this. I too have become very rageful. I scream profanities in my husbands face and slam my first on the counter and I am NOT like this normally, I’m a docile, empathetic person. Not an angry malicious person that Wellbutrin has made me become. I quit. Yesterday. Thank you.
Thank you. For this. I too have become very rageful. I scream profanities in my husbands face and slam my first on the counter and I am NOT like this normally, I’m a docile, empathetic person. Not an angry malicious person that Wellbutrin has made me become. I quit. Yesterday. Thank you.
I was started on Wellbutrin two months ago. I noticed my sadness decreased slightly, but I became more agitated about things. I slammed a door once, and now I have pushed my boyfriend once. I’m scared to switch medications but me being physical just is not me. It was weird because when I did it, I wasn’t even the angriest I’ve been at him. It was just like an outburst of anger. I feel awful about it. And I just wish I could find the medicine that could help me, and in turn help my relationships with the people I love. Also this medication does not decreases my appetite at all like they claim does. I noticed that since on it, I have been eating more.
I took this to help quit smoking. It was working for that purpose but my mood change and issues with anger and aggressiveness destroyed my relationship causing my fiancé to leave me, from which I still haven’t recovered from going on two years. If anyone taking this has these issues I explore you to talk to you doctor about alternative drugs. It’s not worth taking bupropion if it’s going to ruin your life.
I've just started taking a very low does of Wellbutrin and I am also taking 40 mg of Celexa and found that I have a very short fuse and feel angry but didn't put the connection together until my husband said that for the last month I haven't been the same and am angry all the time, I even pushed him.
I have been on Wellbutrin Xl 150mg for 2 weeks now, and have had more negative effects than good. Irritability, insomnia, and absurd anger outbursts have been the worst side effects yet. How is this suppose to help me feel better when I am in a constant anxious, elevated state, lacking more sleep, and feeling awful about myself after getting angry over stupid things?
This feels very counter-productive. Although, it has only been two weeks, so I am hoping these symptoms are short lived. I will give it more time, but this is effecting my work and personal life.
Antidepressants can increase the intensity of symptoms over a few weeks after therapy is initiated ~ they don't work like taking a Tylenol for a headache. It usually takes about 4-6 weeks to feel the full benefits of the medication and it's also usually well worth the time and patience.
Good luck and beat regards,
It's now commonly known that antidepressants can provoke hypo/manic episodes in some users... often characterized by anger and irritability.
These behaviours should be reported to your doctor immediately.
I thought it was just me !! My aggressive ways were so bad my Doc put me on risperidone(antipsychotic) to calm me down... what a nightmare! after 2 doses i felt like i had drunk a bottle of whiskey i was so out of it! Never again.i also have upped my prozac to 40mg so i hope the combo of Wellbutrin 150mg and prozac 40mg works... so desperate now, anxiety disorder has gone crazy but valium helps twice a day... i think i will.just try breathing exersizes/hard exercise/ and meditation to help with the aggressive urges.Im so glad i found this site,i thought it was just me.
Related topics
Further information
- Wellbutrin uses and safety info
- Wellbutrin prescribing info & package insert (for Health Professionals)
- Side effects of Wellbutrin (detailed)
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