Is it OK to take Tramadol and Cymbalta together?

I have had a traumatic brain injury back in 1989... was in a rehab for 6 months... I have been on all kinds of antidepressants since then... 4 years ago I went to a pain management clinic for my severe back pain... After my 1st visit they prescribed tramadol... that night took my meds and 3 hours later woke up on the floor... hit my head badly (blood) and couldn't move my legs... ended up in the ER///when i came home I did quite a bit of research and found a neruoscientist that NEVER should tramadol be given to anyone with a history of head injury... My daughter just had knee surgery and came home with tramadol... she is on antidepressants... and I told her to get off the tramadol... What the hell is wrong with our medical community... VERY UPSET !!!

I think y'all just saved my life!!! Having a terrible time but knowing it could be the drugs and not me is a relief

I currently take both of these medications for Fibromyalgia and have been for a year and a half. I have always experienced restless legs since taking these medications, which is a symptom of Seritonen Syndrome and last week, for the first time in my life, had a series of seizures. Yes, it's rare like the literature and doctors report, but entirely possible to occur even after 17 months of continued use. I know this thread is old, but I wanted to share my experience :)

Yes. In my case, I used them both simultaneously & then later stopped the Tramadol & increased the Cymbalta. LenOw, it's good to ask questions like these to become better informed. In addition to the information that you can find here on Drugs.com, remember you also have access to your pharmacist's knowledge which is a valuable resource. Good luck to you!

Hi, i wanted to add the link to the interactions checker so that you can be aware of any symptoms to watch out for. It does seem a bit scary, but please don't worry too much. I used to take Tramadol alongside SSRI's and i was absolutely fine. But you should know the facts just to be safe...
https://www.drugs.com/interactions-check.php?drug_list=2221-0,949-2273

Yes, only if they're prescribed that way. The Dr should know about both and should advise you what is best for you, as we all react differently, especially to Cymbalta.

Yes, though there is a warning concerning serotonin syndrome this is very rare and at the levels you are taking not likely. I suspect the doctor is hoping that the Cymbalta will help your pain so that you don"t have to continue the tramadol in the future.