I suffer from nerve pain resulting from a failed back surgery. Recently I noticed that my pharmacy had substituted duloxetine for the prescribed Cymbalta. Concurrently, I noticed a higher level of pain. Could it be that Cymbalta’s efficacy is higher than duloxetine?
Efficacy of Cymbalta vs duloxetine?
Question posted by Attilio Galli on 12 Jan 2021
Last updated on 13 January 2021 by todance
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3 Answers
I found that the duloxetine was not as effective as Cymbalta. I was taking cymbalta for nerve pain resulting from a cervical fusion. The relief was not enough to outweigh the side effects until my pain management doctor added Lyrica. For me, lyrica and cymbalta together provided the relief that I had been hoping for.
Duloxetine is generic Cymbalta. There should be no difference between the two. I would talk to your pharmacist about your additional pain and see if switching back to Cymbalta is possible. There are recognized cases where the generic doesn’t work as well as the branded medication... perhaps this is one of them. Talk to your doctor also about this.
I'm sorry to hear you're still suffering.
I too had 2 operations on my lumbar spine for stenosis and disc hernias, I now have metalwork. But, the problem is spreading up and down my spine, now affecting both cervical and sacral regions.
For me neither of the drugs work. Nothing does (only perhaps morphine, but they don't really want to go that far). Speak again with your specialist. I hope they find something to give you at least some relief.
Related topics
cymbalta, peripheral neuropathy, osteoarthritis, pain, back pain, neuralgia, duloxetine, chronic pain, surgery, pharmacy, prescription, nerve
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