I am currently slowly tapering off Cymbalta by counting beads, 3-4% every 4 weeks, currently at about 17mg. My Doctor wants me to stop taking it and start taking Pristiq, another SNRI. I'm afraid of stopping the Cymbalta cold turkey for fear of withdrawal symptoms. I never intended on taking another antidepressant because of the horrible side effects but I am extremely depressed and have bad anxiety which seems to get worse with every drop I make with Cymbalta. Is it safe to start a low dose of Pristiq while still slowly tapering off Cymbalta? Very concerned about serotonin syndrome. I'm not sure if my doctor (Psychiatrist) has the best answers. I'm scared and need help. Thank you all.