Hello. I started on Sertraline 18 years ago and worked my way up to 200mg and stayed on that dose for 15 years. Totally anxiety free and feeling brilliant every day. Then they pooped out overnight and stopped working. Psych added Mirtazapine and have spent the last 3 years trialling combinations of dose but I’m realising that Mirtazapine is keeping me ill and causing all sorts of problems. I want to stay on the sertraline and taper slowly off Mirtazapine and try something else. Has anyone combined Sertraline with another AD and had success and felt better again?
Sertraline combination successes?
Question posted by SallyCinnamon7 on 7 Feb 2021
Last updated on 11 February 2021 by 0756
I have also been on Sertraline for a number of years at 150 mg. I have had PRN's added for nighttime that supposedly gives added benefits through the day. When adding another AD, your risk of SS greatly increases, so that is something to keep in mind. If you are having a poor sleep that can cause anxiety to be worsened/less manageable, would discussing with your doctor sleeping medications be another option to try to elevate your heightened anxiety?
I have been off-label prescribed atypical antipsychotics to accompany my Sertraline however I don't recommend it because of the side effects. trazodone is a commonly added AD for nighttime but some people don't like the sedation feeling.
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