I've recently been put on 300mg Seroquel XR which I take once at night to compliment long term use of Seroxat for anxiety. The Seroquel seems to be working really well for the anxiety but my weight has increased rapidly. Since I started on the Seroquel only a few weeks ago I have put on about 8lbs. I'm a bit of a weight control freak so for me this is a disaster. Does anyone have any experience of this? How can someone control weight gain while taking Seroquel?
Seroquel XR weight gain?
Question posted by toffeeman92 on 31 Aug 2010
Last updated on 12 March 2022 by Mjsofa
I gained weight on XR. I was also tired and hungry all the time on it. I went off it. I felt it didn’t help my insomnia at all. Good luck
Hi, I’ve been on Seroquel 200 mg for 2 years now. Recently, my Doctors changed it to Seroquel XR. I take 200 mg nightly. I’m 61 years and have bipolar 1 and GAD. I’ve gained 5 pounds in 1 week, but I’m finally sleeping. I feel like a rock in a hard place. I also suffer from major insomnia and Zolpidem and diazepam are not enough hence the XR. I’m very petite and eat right. My exercise is limited due to my chronic lung disease and RA. Any help or ideas
It can definitely cause the weight gain originally I gained lots of weight on Seroquel
xr because it made me hungry and I just ate lots of crap or that cuz I was always hungry now I've learned that I have to eat healthy snacks like apples and salads and fruit and or whatever I need healthy lean proteins and meats and exercise if you don't eat healthy while on this pill or exercise at all you will like most likely gain weight if you turn to the wrong foods. I've been on Seroquel XR200 for at least six or seven years if not more. it's hard to stop eating on it since after I have a meal even if I try to eat slowly I'm still hungry later. Causes me to sleep more too which might be causing hunger as well. You have to try to pick more filling foods for breakfast like an omelette or something and more filling foods for lunch and dinner and snacks so you're not always reaching for something unhealthy.
I took seroquel when i was 11, i was 110 pounds at the time, within 8 months i was 220 pounds. i was taken off of it and never have touched it again.
I hate to say I know from experience 30 lbs later. I didn't know about it until I looked it up where? here! It causes increased appetite and the topper is; we all take in the evening due to sleep effects. What a great time to be gluttonous (Well, in my experience) I have to do my best to stay active to compensate. You can beat this monster! All like drugs are the same. It varies on the strength of the effect. I just don't feel like weighing all of the pros and cons. Good Luck!
i started this drug a year ago. In that year i am not only thirty pounds overweight but also have tremendous water retention. this has nothing to do with food as i have a neurological disorder that makes eating solid foods very difficult. my neurologist put me on this thinking a small 25 mg dose would not do this. i have a new doctor now and he is weaning me off- i will be off in three weeks. This drug is a nightmare and what it did to my body is terrible. Also for those of you who think it is food related- i did four months of weight watchers before deciding to get off the drug as i wanted to see and guess what I GAINED WEIGHT! I pray that my body will return to normal weight when i am off it.
As Carli says, every individual reacts differently to every medication. Personally, I have taken many psychotropic medications over the years looking for the right combination to control my Bipolar ll/anxiety/OCD and never suffered a side effect beyond a mild headache or nausea when starting a new drug.
Some people DO have severe side effects but it shouldn't scare people off what their doctor prescribes because, like me, the vast majority of users don't have any side effects that inconvenience them, and only enjoy the benefit of a a happier, healthier life.
BOTTOM LINE-Every individual reacts differently to every medication and we can only give our own experience. But you won't know until you try it and that is the scariest part. I call it guinea pigging!!! My experience with Seroquel, 20 years ago they gave me 300 mg. I took a quarter of the pill when my kids were young and slept for 3 days. Scared the crap out of me and quit that first time. I am now 49 and the past 3 weeks i have been taking 25 mg a night it knocks me out i sleep in 2 hour intervals but wake up a bit groggy and definitely am gaining weight!!! I hardly eat, never have, am 5'4 and about 120lbs. and after 3 weeks up to 137lbs. still hardly eating and exercise daily. That is a ridiculous amount of weight gain. My opinion definitely medication. I am now stopping medication to see how long it takes for weight to come off and trying trazodone. Ughhhh. Guinea Pig for Life...
I have been on Seroquel for 7 weeks, I am a recovering anorexic/bulimic, I am gaining a lot of weight in my middle, now my clothes don't fit, I eat well and work out, I am afraid this medication is just going to have to go away, I just put a call in to my psychiatrist as this extra weight is making me depressed.
hi toffeeman92, im manic depressive and have bad anxiety im on mirap 45mg(mirtazapine) and in the past 6 months my depression got worse so the increased my Seroquel from 200mg xr to 300xr iv ballooned out i used to be skinny now im huge and i dont eat that much food and when i do its healthy all my clothes are gone from a size 12 to 3xl baseball tops ,my arms and legs are skinny its just my stomach ,i wont even go to pubs or nightclubs anymore i hate it does anybody know another ssri or ssni that i could change to that doesnt cause weight gain its ruining my life iv no confidence and its ruining my life and i dont know what to do ,iv my best friends wedding coming up im maid of honour and il look horrible in a dress :(
I was put on quetiapine two years ago and have gained about 35 pounds to my horror. I am heavier than I have ever been in my life. I have reduced them gradually so I'm now on a low dose but haven't lost any of the weight yet and I now have chronic insomnia. Any tips on how to lose this weight please? Feeling desperate.
My child started on seroquel 300 recently. He has gained 20 lbs over the last two months. I am beginning to worry about the long term effects of the drug and if there are other options. One of his doctor did mention that I have put him on an exercise program. So I guess I now have to weigh the pros and cons.
Again I'm late to the party but I will say if you have anxiety or depression and are conscious of your weight then get the heck out of dodge before it's to late. I've been on Seroquel for 6 yrs and weaning off for last 2. I gained 60 lbs on a 99 lb body. If anything this made my anxiety and depression worse. I had to take cogentin because I was stuttering and biting my tongue. My memory is awful. Thank G-d the TD went away as the dose went down. I was lucky. Now I'm forced to take Topamax. Oh well. Hope it's not as bad as Seroquel was. The Topamax is for my Migraines but may help with mood to and neuropathic pain of RSD which I have so sorry I digress. Talk to your Dr about concerns
I've been taking SEROQUEL XR approximately 4 or 5 years. I had gained weight due to several factors, one being major water retention due to an underactive thyroid. Once diagnosed and treated, I lost a significant amount of weight, including dieting. However, I gained weight last year after I got a pacemaker and was put on a second heart medication, which caused weight gain. Needless to say, I was far from being happy. I had my annual physical the end of June. My internist mentioned the "excessive" weight gain but discounted that medications have anything to do with it. This is an added reason why I try to be as educated as possible about my medical conditions, including prescription drugs. It is what it is. And as long as the psych and cardiac meds are working, I continue to go with the flow. And if the internist continues to have a problem, then he can contact my psychiatrist and cardiologist.
First, I must save that the Seroquel actually saved my life. I was undiagnosed Bipolar and was in the hospital 6 times in 12 months for suicidal thoughts / attempts. I was unable to function at all, and a lot of it was that I wasn't getting a good sleep at night. I get a great night's sleep every night with Seroquel. My psychiatrist gradually increased my dose to 600mg per day, and my mood is now stabilized, and I can work again. I noticed that I was gaining weight (the psychiatrist never mentioned this as a side effect), but thought it was just because I was overeating. But now I realize it was the Seroquel. I was already overweight, and added on 30 more pounds. None of my clothes fit now, and the excess weight makes me self-conscious.
But hey--ANYTHING is better than being in a mental hospital against your will! That being said, recently I have altered my diet to an Atkins-like menu consisting of lots and lots of protein and fresh vegetables, but nothing made from grains (except for high protein quinoa), absolutely no gluten, no sugar or honey or artificial sweeteners, no high-glycemic vegetables such as corn or potatoes, and very little fruit (because it has sugar). I have gradually lost 12 pounds, and my total cholesterol has plummeted from the low-300's to 161. I'm really happy about that! But, it is a very hard diet to stick to, and I keep hearing the rumors that you cannot lose weight on Seroquel, no matter what.
I've read the suggestion that people on Seroquel take amphetamine-like weight loss pills, but I think my problem is the Seroquel, not my appetite. I don't think eat any more than I did before; if anything, I eat less. I think my metabolism is altered. In addition, I am taking six other medications for everything from blood pressure to depression to breast cancer. The idea of asking my liver to work even further overtime to filter out all of these meds scares me. I need to be absolutely sure that I am stabilized on my meds before I consider making any other changes, other than the previously-mentioned diet changes.
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