Safest SSRI or SNRI to use with Adderall??

Just to add my two cents worth. Pristiq must be taken on a daily basis to be effective. You can't just take it occasionally It won't work and you'll be wasting a lot of money.
Wildcat

Hello,

Two Major Interactions between Adderall and Pristiq, major meaning:

Major Highly clinically significant. Avoid combinations; the risk of the interaction outweighs the benefit.

Interactions between your drugs
Major
amphetamine desvenlafaxine
Applies to: Adderall (amphetamine / dextroamphetamine), Pristiq (desvenlafaxine)

Talk to your doctor before using desvenlafaxine together with amphetamine. Desvenlafaxine may increase the effects of amphetamine, and side effects such as jitteriness, nervousness, anxiety, restlessness, and racing thoughts have been reported. Combining these medications can also increase the risk of a rare but serious condition called the serotonin syndrome, which may include symptoms such as confusion, hallucination, seizure, extreme changes in blood pressure, increased heart rate, fever, excessive sweating, shivering or shaking, blurred vision, muscle spasm or stiffness, tremor, incoordination, stomach cramp, nausea, vomiting, and diarrhea. Severe cases may result in coma and even death. You should contact your doctor immediately if you experience these symptoms while taking the medications. It is important to tell your doctor about all other medications you use, including vitamins and herbs. Do not stop using any medications without first talking to your doctor.

Major
dextroamphetamine desvenlafaxine
Applies to: Adderall (amphetamine / dextroamphetamine), Pristiq (desvenlafaxine)

Talk to your doctor before using desvenlafaxine together with dextroamphetamine. Desvenlafaxine may increase the effects of dextroamphetamine, and side effects such as jitteriness, nervousness, anxiety, restlessness, and racing thoughts have been reported. Combining these medications can also increase the risk of a rare but serious condition called the serotonin syndrome, which may include symptoms such as confusion, hallucination, seizure, extreme changes in blood pressure, increased heart rate, fever, excessive sweating, shivering or shaking, blurred vision, muscle spasm or stiffness, tremor, incoordination, stomach cramp, nausea, vomiting, and diarrhea. Severe cases may result in coma and even death. You should contact your doctor immediately if you experience these symptoms while taking the medications. It is important to tell your doctor about all other medications you use, including vitamins and herbs. Do not stop using any medications without first talking to your doctor.

Report:
https://www.drugs.com/interactions-check.php?drug_list=190-1645,2796-12488

I am not a medical professional, having said that your DR. is responsible for your treatment and above all your safety.
I suggest you do not take Pristiq until you have spoken to him/her and clarify these potential major interactions.

FYI, interactions of all 4 medications:
https://www.drugs.com/interactions-check.php?drug_list=233-109,190-1645,1147-0,2796-12488

All the best, masso