I'm currently on methotrexate but have completed a 6 day water only fast and am currently on a very restrictive diet to see if I can snuff out this Rhuematoid arthritis. Is there any harm in backing off the meth to see if the pain is gone? If the pain is not gone, I would kick it back up to my prescribed dosage. I'm just curious, if I don't stop at some point, how would I know if the pain is still there? or know if what I am doing, is working to reduce or eliminate my need for the meth? Currently I am on 25 mg oral along with 3 mg folic acid( mouth sores with less) I cut my dosage in half after my water only fast. It's only been 5 days. If the pain in going to come back, how long would it take likely. Is there any harm in doing this. Curious minds want to know.