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Will Ranitidine (Zantac) cause you to fail a Drug Test?

11 Answers

Ddutton69 5 Oct 2019

Yes it will show a false positive for marijuana

Votes: +0
Psielite 15 Feb 2019

Absolutely! I conduct drug screens for work place investigations and am a drug screen analyst. I use ranitidine (ranitidine hydrochloride) 150mg 1-1.5x a day for acid reflux and I tested positive for methamphetamine's on an express (urine) test that we conducted as a random control, 12 panel test, knowing without a doubt it should return a 100% negative result for drug use.
The first time this happened we actually initiated an investigation to determine if our staff was being drugged for nefarious reasons before we were advised of ranitidine's proclivity to show false positive non-negative express test results.

Votes: +0
Amulyn777 5 Jan 2018

Yes! I had a urine test today. Never touched amphetamines in my life! It came up positive and I looked up what could cause a false positive. Thank God it showed Zantac/ Ranitidine. I took 150mg this morning, two hours before my drug screen. Crazy! Carry all prescriptions with you next time. And if you must, try to educate your professional.

Votes: +0
Stephanie4176 13 Nov 2017

I have been clean a little over 11yrs an I get drug screens every month in my sobriety program. I hv had over 11yrs of clean UA's except my initial one to enter program. This past Monday I had a drug screen an on Thursday I got a call I tested positive for amphetamines. It's impossible because I have been clean from illicit drugs. I recently started taking ranitidine 150mgs otc an now I am finally aware that this is the culprit. I am loyal to my sobriety. I really wish they would put info in the leaflet so we are aware of it.

Votes: +0
Nadzaroni 18 Aug 2017

YES it Does! It just made me give a false positive for methamphetamine, I'm 9 months pregnant and I'm completely drug free. I would avoid taking this medication if you have a UA coming up.

Votes: +0
RebeccaBrummel 10 Aug 2016

Yes, it will. It just happened to me. I have been using pretty large amounts of Zantac, for years. When my employer very recently gave me a random, on the spot urine drug test, I came back positive for methamphetamine! - a substance I most certainly do not use! Nor have I ever.

The pharmacist, at my Physicians office told me, and my employer, that it was the Zantac causing the problem. An extremely embarrassing problem, I might add!!

Votes: +0
taunya69 31 Aug 2015


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mommaxxx 8 April 2015

I am almost 7 months pregnant and my doctor had me start taking zantac and I had to drop for my po and it came back positive I have not done any drugs and freaked thinking the mixed up my pee with someone else's so yes it can

Votes: +0
ericpotter2002 15 Dec 2012

Yes absolutely ranitidine can cause a false positive for meth. i recently failed a urine test. Said i used meth. Not possible! I took 1 ranitidine 150mg about two and a half hours before my drug screen. The only other drugs i took were ibuprofen and rolaids. I really dislike all medication. Thankfully my employer allowed a confirmation test. A hair test proved my innocence. Still it cost me several hundred dollars in lost wages. Personally i will choose to suffer the unbearable stomach pain rather than risk my job again.

Votes: +2
Miss_Jes5ica0414 16 Oct 2013

I am going to agree... I am 7 months pregnant and I have been taking ranitidine 2-3 daily because how bad my stomach burns and my docotors office just called me telling me I tested positive for methanphetmine !!! IMPOSSIBLE! But I also found this information on another website about it making her fail for meth too!!!

jeffrothegreat1 11 March 2015

listen to this person they are very very right and i know cause today it happend to me and i almost crapped myself 3/11/2015

jenniferobryson77 8 Dec 2016

I have recently just failed one because of ranitidine myself. And it is causing me problems as well. I was wondering how the confirmation hair test worked to your advantage? Was it just the hair follicle itself or did you have them look for the ranitidine? If you don't mind me asking. It could really help my situation to know.

Hamerrhonda 23 Jan 2017

I've been taking ranitidine for 10 days prescribed by Dr for stomach virus and just went to drop a urinalysis and it came back positive for meth..not funny!

Inactive 4 Dec 2012

ranitidine - Can Cause False Positives For Amphetamines.

Votes: +1
kaismama 4 Dec 2012

I suspect it could. Other medications like it have. These drug tests are not accurate, and many prescriptions and otc meds can cause false positives, not to mention food.

Votes: +0 free discount card

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zantac, ranitidine, drug test, urine test

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