Is it ok to take pristiq and mucinex dm?

Ask your Doctor before you take Mucinex dm with Pristiq or any kind of med's make sure they want interact, side effects can be bad.

Interactions between your selected drugs

dextromethorphan ↔ desvenlafaxine
Applies to: Mucinex DM (dextromethorphan / guaifenesin), Pristiq (desvenlafaxine)
Talk to your doctor before using dextromethorphan together with desvenlafaxine. Combining these medications can increase the risk of a rare but serious condition called the serotonin syndrome, which may include symptoms such as confusion, hallucination, seizure, extreme changes in blood pressure, increased heart rate, fever, excessive sweating, shivering or shaking, blurred vision, muscle spasm or stiffness, tremor, incoordination, stomach cramp, nausea, vomiting, and diarrhea. Severe cases may result in coma and even death. You should contact your doctor immediately if you experience these symptoms while taking the medications. It is important to tell your doctor about all other medications you use, including vitamins and herbs. Do not stop using any medications without first talking to your doctor.

Other drugs that your selected drugs interact with

Mucinex DM (dextromethorphan / guaifenesin) interacts with more than 50 other drugs.
Pristiq (desvenlafaxine) interacts with more than 400 other drugs.

Interactions between your selected drugs and food

No results found - however, this does not necessarily mean no interactions exist. ALWAYS consult with your doctor or pharmacist.

https://www.drugs.com/interactions-check.php?drug_list=846-8245,2796-12488