Getting weaned off prednisone and have palpitations .I am on 25 mg now. I get them in the am and then they subside to occasionally during the day. I had an EKG done and it came back abnormal . Dr said there have been some changes since my previous EKG. I do have heart issues with blockage in left main coronary 50-50% blocked.. Wonder if the prednisone is the cause of these palpitations..Had another EKG today and they said it was better but still not ok. See heart dr in 3 weeks again for another EKG. If palpitations persist may have to go to ER Dr may do a stress test. Wondering if this is med induced ie: prednisone or the methotrexate I am taking.