When I fill my monthly generic prescription for oxycodone, I sometimes get pills made by different manufacturers. It seems like some work better than others, same dose - same drug! Does anyone else have this experience?
Oxycodone - Is there a difference in manufacturers of generic drugs?
Question posted by Anniebananie12 on 1 July 2013
Last updated on 10 July 2022 (12 weeks ago) by Reece131
YES, manufacturers of generic drugs are different. Although sometimes you will see a manufacturer requests a change to a drug under another name and when you do some digging, you find they are the same. Like Rhodes... it has several other names it uses to get changes approved to their drugs. You think people are overdosing on opioids. However, anyone who has had to take pain meds for long periods of time understand that not all opioids are alike. So imagine being in excruciating pain and your refill being a manufacturer that uses more fillers and those fillers make the drug less effective. A person that has no voice could take more and more just waiting on it to work. Not because they are trying to hurt themselves, but because they are trying to just have a pain free moment. Go with what you know… If you have taken something you know works, fight to keep it. You are the only one who knows how you feel.
I think they are different. The blue oxycodone 30s are way stronger feeling then the yellow ones
I get my meds through the 3-letter pharmacy (not sure if we can use the names) and in my past experience they typically only use Malinckrodt (sp?) and one or two other manufacturers. I honestly didn’t see any difference in the generics I was dispensed. Just wanted to add my experience as I’m guessing that most of those who respond will say there is a difference. I didn’t experience side effects or changes in effectiveness. They usually kicked in for the pain after about 30 minutes and lasted 4 hours. Never had one last a whole 6 hours. Also, never was dispensed the Percocet brand name so I can’t compare generics vs brand name.
Basically your asking, what’s the differences in oxycodone.? Because so many versions are many by many companies. Let’s say this, we know that
There’s many of the same dose
10mg oxycodone/325mg Tylenol “Percocet” made by a company that designed this pill round with a cool imprinted C on one side and 320 on the other colored yellow. If we want to compare that 10mg/325mg Percocet, to say, a white capsule shaped this time with imprint IP204. They may look different but that example is two different pills, but in actuality they were exactly the same Exact active ingredients.
10mg oxycodone & 325mg Tylenol.
They should be zero difference in the amount between the two, and the only thing that is legal to be different by lay is the fillers and bindings to make the pill itself.
The medications are not the same. The oxycodone and hydrocodone vary in strength from manufacture to manufacture. The government, the doctor's and pharmacist all know this is taken place. The pharmacy will generally accept the cheapest price they can get. Unless consumers complain about a certain product, nothing will change. This started many years ago when all the lawsuits were filed and are still being filed. Until very recently I was able to get the yellow V 36 01 made by Endo thru merger and buyout. Good quality will be hard to find. Some pills do work better than others, not by much.
I've had that happen with oxy and soma a couple of times over the years. If you have been going to the same pharmacist for a long time, you should just bring it to his/her attention. And, sometimes they can go to a different manufacturer. Because of people who truly have conditions that require these trusted medicines, our wonderful dictator government has been limiting the manufacturers that pharmacies can order from. It was never like this years ago. But, it's just another tactic to try and continue to punish citizens and, the pharmacies that actually still try to help their patients. Which is what they were trained to do for years. But, if you have a good pharmacist, they usually will try and change to another company. Let me know
Yes I feel when pharmacy switches. I don't get as much relief with most... but the cost for Brand name ... I sure can't afford...
NOT ALL PERCOCET IS CREATED EQUAL! WHY GENERICS ARE INFERIOR
All Percocet is made with the same ACTIVE ingredients; BUT NOT ALL PERCOCET is made using the same FORMULA.
FORMULA is the KEY. Here is why:
The FORMULA consists of all the INGREDIENTS used to make each pill, AND NOT ALL MANUFACTURERS USE THE SAME FORMULA.
To maximize profits, pharmacies buy the cheapest drugs they can find. In order to make the cheapest drugs, manufacturers simply leave out certain ingredients.
Anytime a manufacturer leaves out ingredients, THE DRUG WILL NOT WORK as it was originally designed to work.
By law, generic drugs sold to the public only have to contain the ACTIVE ingredient. They do not have to contain the original formula that the original drug maker spent years and billions of dollars on to ensure that the drug worked properly.
The missing ingredients are what often act as a DELIVERY SYSTEM. Delivery systems are developed to insure that the drug gets absorbed into the blood stream in a very specific way. It may ensure the drug gets absorbed quickly, or it may prevent the drug from being digested too soon, as some drugs only work when they are absorbed further down in the digestive tract.
WHAT YOU CAN DO:
Tell your provider that you want the BRAND NAME drug, not the generic. Often, the brand name is the same price, as it is for Percocet. Ask your provider to write for ENDOCET or PERCOCET, and to put NS, or “No Substitutions” on the Rx. Just be prepared for when the pharmacist tells you, “We don’t have those,” or “We will have to order those,” or “We can’t get those.” Find a pharmacy that can or does.
Patients should be treated honestly, not just as a source for turning poor quality drugs into cash.
Absolutely there is a difference. Some are oblong white some are round yellow. My pharmacy switched manufacturer after 12 years and now all of a sudden this month I have developed severe feet edema and that's NEVER happened in all the years I've been on it until it came from different manufacturer.
I had this experience. After the NY State Attorney General enacted a law to tax opioid medication, my pharmacist had trouble ordering the usual oxycodone tablet. (Prior to this, I never had a problem with pain control, therefore never checked manufacturer). The tablets were small round light blue 30mg oxycodone immediate release. The only manufacturer the pharmacy was able to order from who would ship to NY was Rhodes Pharmaceutical. Their tablets were bigger round white tablets. I had no relief from the pain with Rhodes tablets. When I looked into Rhodes, I discovered that they are owned by the Purdue pharma company who marketed their OxyContin to teenagers for sports injuries! Oxycodone should be used by chronic pain sufferers and end stage pain issues. As I said I never had a problem with the efficacy of the medication so I contacted the FDA. The form they have for complaints about medication products can now be filled out online.
I did so and fast forward a year or so, the pharmacy was dispensing the small blue round tabs again. I noticed that the pain was lessened and the difference was like night and day with both the white and blue pills. Yes, when I saw that Rhodes manufactured the blue round pills after I filed the complaint with the FDA, I was shocked. I don’t know what to think. Did my complaint and many others lead to an investigation and improvements? I don’t know. But if you are having issues with something like medication, the FDA is the agency to contact.
Yes!! Huge difference! When you notice they are NOT as effective, call your pharmacy. You want to get some information from them.
1. Pharmaceutical company that made them;
2. Lot number off the bottoe:; AND
3. Expiration date.
File with them & pass it ON! There's a few companies that screw around & they'll have keys say china make the drugs. China will lie about how much is in there.more profit
I've found that with oxycodone for years.
The Auro Oxycodone 10mg U17 are terrible and they were recently recalled, or a certain batch and NDC number were. I am actually having mine tested by a lab that specializes in doing so, they made me extremely ill and I aim to find out why. Feel free to contact me.
I realize I am answering a really old question , I apologize. But the U17, is not effective at all for me, as oxycodone. Not sure why. It even gives me heart palpitations. Please advise, if you can and let me know your thoughts if you have had others not be as effective. Thanks so much, Carrie.
Say what you will but from experience there is a difference from generic oxycodone its not as effective and does no work as long , about half as long non generic .
- Oxycodone uses and safety info
- Oxycodone information for Healthcare Professionals (includes dosage details)
- Side effects of Oxycodone (detailed)
Search for questions
Still looking for answers? Try searching for what you seek or ask your own question.