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Can I take nortriptyline and Trintellix together?

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WildcatVet 12 Dec 2018

Hi, Sandy! There is a slight risk of a rare disorder called serotonin syndrome so this combination should only be taken if prescribed and monitored by your doctor.
"Using nortriptyline together with vortioxetine can increase the risk of a rare but serious condition called the serotonin syndrome, which may include symptoms such as confusion, hallucination, seizure, extreme changes in blood pressure, increased heart rate, fever, excessive sweating, shivering or shaking, blurred vision, muscle spasm or stiffness, tremor, incoordination, stomach cramp, nausea, vomiting, and diarrhea. Severe cases may result in coma and even death. You should seek immediate medical attention if you experience these symptoms while taking the medications. Talk to your doctor if you have any questions or concerns. Your doctor may already be aware of the risks, but has determined that this is the best course of treatment for you and has taken appropriate precautions and is monitoring you closely for any potential complications."

Votes: +1
Sandybrowne 12 Dec 2018

Thanks alot. I had read that in several different places. I had read also that one is to treat the symptoms of depression and the Trintellix was for depression itself. So I just assumed it would be ok. So grateful I ask the question. I'm calling my Dr today. Thanks again.

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