I take Metoprolol Succinate is it ok for me to take Metoprolol Tartrate ?
The difference is that Metoprolol SUCCINATE slow releases your full daily dose over a 24-hour period, so you only need to take it once a day, .. whereas, Metoprolol TARTRATE releases over a 12-hour period, .. so you have to take tartrate twice a day with each dose being half of the total daily milligrams you need.
Metoprolol Succinate typically costs more than tartrate, but succinate is less hassle since you can simply schedule to take it once-a-day with one of your regular meals.
Bottom line is that the number of milligrams prescribed to you by your doctor is the DAILY dose amount that you're supposed to take. So if your doctor gave you a prescription for "X" milligrams of metoprolol SUCCINATE ( which is a "once a day" med ); and then if he/she switches you to metoprolol TARTRATE, each tartrate pill will be HALF the milligrams of the succinate pill because you'll need to take TWO tartrate pills per day, .. so you end up with the SAME TOTAL NUMBER OF MILLIGRAMS per day.
Four years ago, my doctor prescribed that I take a 25mg tablet of metoprolol tartrate TWICE a day, which gave me a total of 50mg per day. Since you're supposed to take metoprolol with food ( to slow down the absorption rate ), it was just too much hassle because I don't normally eat food 12 hours after any other meal in a day. I finally remembered to "complain" to my doctor about having to take the tartrate with food twice a day, so he switched my prescription to a once-a-day 50mg dose of the succinate ( which still should be taken with food, but at least I can now simply schedule it with one of my regular meals ).
Anyway, as you can see, THE TOTAL MILLIGRAMS PER DAY STAYED THE SAME, so that's what's important.
The reason I was looking at these questions/answers about metoprolol, in the first place, was because I wanted to know if there's a difference between the SIDE EFFECTS of succinate versus tartrate .. or if one is more prone to side effects than the other. Just a few minutes ago, I gave up on trying to find an authoritative answer to that and decided to call a local pharmacist. .. .. ..
.. .. she said that, in general, side effects, if any, are more likely to occur with quick-release doses because they "spike" and "dip" in your system more than slow-release pills do; .. so, since slow-release medications release more evenly into your system, they're tolerated better by most people. She said that occasionally someone will mention they experience a little dizziness with the metoprolol tartrate. I added that I'm most interested in long-term side effects, for instance, is either the tartrate or succinate more prone to causing kidney or liver damage. I was told, "No, the only difference is in how they release, but they're both the same chemical, so they're both the same with regards to long-term effects."
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Posted 8 Nov 2014 • 2 answers
When changing from Metoprolol succinate, 25 mg. daily, to metoprolol tartrate, what dose is correct?
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