For several yrs I took 100 mg/day. BP was very good. I gained about 15 lbs in the last 3 yrs, but this yr my BP went way up. Dr. Increased dose to 200 mg/day, but it has made no difference. I have a Dr. apps in 4 days. But wondering if your body can build a tolerance for metoprolol? Is there some other drug that might work better? I have been on several different meds as it has been high for 40 yrs. Kind of concerned that maybe nothing will work. I don't like the 200 mg. dosage because I am tired all the time.