Methylprednisolone - By the 2nd day of a 6 day pack, should I be getting relief from sciatica?

Sciatica refers to pain, weakness, numbness, or tingling in the leg. It is caused by injury to or pressure on the sciatic nerve. Sciatica is a symptom of another medical condition so the underlying cause should be identified before treatment commenced.

A herniated (slipped) disk occurs when all or part of a disk is forced through a weakened part of the disk. This may place pressure on the sciatic nerve.

The first treatment for a slipped disk is a short period of rest with medicines for the pain, often NSAIDs (non-steroidal anti-inflammatory drugs) or narcotics for severe pain. Some doctors prescribe oral corticosteroids (methylprednisolone) although the benefits of this treatment are uncertain. This is followed by physical therapy. Most people who follow these treatments gradually recover and return to normal activities within four to six weeks. Some people will need to have more treatment. This may include steroid injections or surgery.

https://www.drugs.com/health-guide/herniated-disk.html

Check with your doctor about taking Valium, short term it should help to relax your muscles and promote sleep. A glass of wine should be fine too but avoid taking along with Valium.