Why when I take my medicine Prozac do I get EXTREME heartburn immediately after I swallow it?

Hi Rita-
See if you can get another manufacturer for your Prozac sometimes that makes a difference. If you still get heartburn, talk to your doctor.
I hope others on this site will respond with maybe some options.
Hope you find what is the cause soon.

I was proscribed Prozac (20mg fluoxetine) a couple of weeks ago and I had the same problem. I have no issue taking any other pills of any size. It's like it would be stuck in my esophagus for days and I felt heartburn right away after taking it. The pills I take are blue capsules and I found a forum online where someone was saying that it's the gelatin capsules that cause the problem. So I talked to the pharmacist and he said I could open the capsule and mix the medicine with food and take it that way. So now I open the capsule and dump it out into a spoonful of sugar free pudding, mix it, and swallow it, and drink water after. No more heartburn! I think you could mix it with applesauce, chocolate syrup, yogurt, anything like that. I just throw away the empty capsule. I hope this helps.