I have three nails involved, on of the them is the big toe. According to the instructions, I will need 4 drops per day. 1 drop each for the small toes and 2 drops for the large toe. I have found that the 4 ml bottle runs out of medicine after three weeks. I am getting about 80 drops out of each bottle, but the pharmacy says there should be 200 drops per bottle. I am not getting close to 200. There is no information provided with the prescription as to how many doses are in each bottle. Pharmacy advises that insurance will not cover more than one bottle per month.