I have been taking Amoxicillin (500 mg every 8 hours) for one year with no stop time as far as I know. The drug is used to prevent repeated cellulitis in my legs which have led to sepsis. I have chronic pedal edema in my legs due to Noonan's Syndrome. I was hospitalized seven times between December 2013 and October 2014. This treatment was the last resort. What are the long term effects of taking this drug? I'm asking because I have recently begun feeling more weak and tired lately. Thanks.
What are the long term effects of using Amoxicillin?
- Asked
- 23 Nov 2015 by frankjacobson
- Updated
- 24 Nov 2015
- Topics
- sepsis, bacterial skin infection, amoxicillin, drug
Responses (1)
As I'm sure you know, antibiotics like Amoxicillin are not usually prescribed long-term. Most side effects have to do with disruption of natural gut flora, and are gastrointestinal in nature. On the other hand, long-term use of the drug may increase your susceptibility to other infections, and reduce your body's ability to fight them.

Further Information
- Amoxicillin Information for Consumers
- Amoxicillin Information for Healthcare Professionals (includes dosage details)
- Side Effects of Amoxicillin (detailed)
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