I was on 50 mg of prednisone for 6 months for a kidney disease called Minimal Change Disease. I started the taper in late July and slowly came down the dose over another 5 months to complete the regimen. I had Cushings while on prednisone, but it pretty much disappeared by the time I completely finish the steroid in late December. Unfortunately, the massive joint and muscle pains I've developed (it started around the time my dose was down to 25 mg) are not going away after 12 weeks of being completely off of the steroid. I was hoping that, by now, these symptoms would be less severe, but that is really not the case. Does anyone have a similar experience, and if so, do the symptoms eventually go away (say, after 6 months or even a year??) Thank you.
How long does the prednisone withdrawal joint and muscle pain last?
Question posted by mod_act21 on 12 March 2021
Last updated on 8 September 2021 by luckywife1990
5 Answers
I was on Prednisone 10mg for 4 yrs and I slowly tapered completely off of them about 2 weeks ago. I tapered off for 4 months. I too have massive joint and muscle pains everywhere and it is really hard to function. I have read it can take up to a year-I don't think I can deal with that. I did wean off steroids once before and had only hand pain and did see a Rheumatologist and she found nothing. She said it was steroid withdrawal. I have Membranous Nephropathy .
Your symptoms check off several on the list describing polymyalgia rheumatica. This vasculitis disease can come on suddenly after an illness, surgery, accident, new medication, or other high stress events. Is your scalp sore? How high can you raise your hands above your shoulders? Any sore throat, ear ache, jaw pains, or vision problems that come and go? How difficult is it to turn from side to side in bed? Does it seem like you are walking in wet cement?
Getting adequate daily calcium, magnesium, natural Vitamin E, D3 and K, and omega 3s is important for muscle and tendon repair.
Has your cortisol level been checked since you are now relying on your adrenal glands to pick up functioning again. Also suggest tests of C-reactive protein and SED rate if they have not been checked since you developed the all over body pain. That will indicate if you need to go back on prednisone at a lower dose to clear built-up inflammation in the muscles.
Thank you adoptmeow for your comment. I just looked up polymyalgia rheumatica, and you are right - my symptoms check off a lot on their list of things to look out for. I do think I need to check my cortisol level (as well as C-reactive protein and SED rate) along with calcium at this point to nail down what is going on. I haven't really paid attention to nutrients for repairing muscles and tendons. This has been SO helpful!! I now have a couple of things I can try and items to discuss with my next doctor's appointment.
Thanks again,
@ adoptmeow :
You make good points and I agree. I will mention that CRP and SED rate do not always accurate due to the manner of testing, equipment used and labs have different reference ranges and therefore 50 % of the time CRP & SED rate indicate no inflammation when in fact the person does indeed have inflammation but I agree the tests should be done as a potential discovery tool. -- pharmacist in Dallas
I have been on moderate to low dose prednisone for three years for polymyalgia rheumatica, and my muscle and tendon pain level is as bad the pain from swelling before I was diagnosed. I've tried methotrexate and leflunomide each for two months and got worse each time. Is there any kind of tests that can determine if the pain is from vasculitis or from prednisone damage? I have a hard time understanding how prednisone can be the only answer to restore mobility and decrease pain, and then be blamed for painful muscles and tendons.
I agree with you. It is perplexing. As far as I know there is not a blood test specific to what you are asking but an MRI is best for revealing soft tissue damage. Prednisone reduces swelling of soft tissues but high dose long term use can cause tendon and ligament damage which is poorly understood. Prednisone is good for short term but you shouldn't take it long term at high doses. Low dose e.g., 4 mg shouldn't cause any problems. What test has your Rheumatologist done ?
Have you had your calcium levels checked out? Because prednisone decreases calcium in the body. “Corticosteroids tend to both reduce the body's ability to absorb calcium and increase how fast bone is broken down. Therefore, which can lead to the symptoms you are having. I’d recommend you getting a blood test, just to see your levels.
Hi Tyrese,
Thank you for your comment. I haven't had it checked lately though I was asked to take a calcium supplement while being on prednisone. I can definitely ask my doc to order me the test.
Thanks again!
You are welcome, take care.
Importantly, your doctor should definitely check your Parathyroid. Since they control calcium in your blood.
Long term use of Corticosteroids can cause joint damage ESPECIALLY tendon issues. Even though you tapered, 6 months is too long to be on corticosteroids. The general rule of thumb is the longer the duration of use the higher the risk of muscoskeletal issues. The only solution besides surgery is multiple light but elongated stretching exercises followed by 8 - 10 hours of quality sleep and the highest quality Turmeric powder you can find and take it before you go to sleep so that it can work while you sleep. It will not cure the condition but it will manage it and it should help you wake up less stiff. I hope it helps.
Hello TR. Thanks for your comment. Corticosteroids sure have a bunch of side effects that my doctors never mentioned... I will incorporate stretching and turmeric. Thank goodness my sleep has not been disrupted (tho my hip joint pains do wake me up in the middle of the night sometimes) so far. Thanks again, TR.
You are welcome
Hi Mod,
I have CKD but i was taking prednisone for a hacking cough 7/24. I forget the dosebut it was high. The first week I was rebuilding the house by 6 months later, I could hardly get your of the bed! This is do the the muscle atrophy.
Everyone is different!
However, I'll fell you what happened to me.
I had 4 months of disease before I started prednisone, on them for 6 months, withdrawal period. And I started to feel better in a little over a year. For me... I'd say I felt sick for the amount of time that I was so sick and then predsone time. I'd say 2:1 time to recover FOR ME.
Do you think you have a new problem with your joints since starting prednisone?
It's a long path and you can't force it. Follow what your body tells you to do.
Be well
:-)
Thank you for your message, Windchimes. I'm glad to hear that your symptoms got better eventually. Definitely gives me hope! I had minor arthritis in my right wrist prior to me taking the prednisone, but it was just a little stiffness and nothing more. Now I can't put any weight on both wrists. My fingers are stiff. My ankles, knees, and hip joints hurt quite bad. My heels and calves hurt as well, which makes it super hard to get out of a chair or a couch + walk uphill. My elbows, too, are tender most of the time. I sure hope I have not developed major arthritis all over... It's been a rough road, but I am keeping my fingers crossed for better days ahead.
Thanks again for commenting on my question. I really appreciate it!
Your response was excellent,!
Patients should know that if they give specifics it gives the doctor a much clearer picture.
I'd treat it as a potential new problem until you get an answer.
I'd recommend going to a Rheumatologist.
If you have anything new, please give us feedback.
Be well
:-)
Related topics
pain, muscle pain, prednisone, withdrawal, dosage, muscle, kidney, disease, taper
Further information
- Prednisone uses and safety info
- Prednisone prescribing info & package insert (for Health Professionals)
- Side effects of Prednisone (detailed)
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