Is it safe to use furosemide in conjunction with spironolactone?

Yes, you are missing something. Nobody has given you the complete explanation. Furosemide or torsemide are strong diuretics. Spironolactone is a mild diuretic. If you take furosemide or torsemide before bed, you will be up all night urinating. By alternating furosemide or torsemide at breakfast with spironolactone after dinner you can sleep. Spironolactone causes you to awaken maybe once during the night. Furosemide or torsemide at dinner won't let you sleep, period.

I have been taking both Spiro and Lasix for a year or so with no obvious major problems. I have CHF and a pacemaker installed last October. However in a recent check on my blood my potassium levels were too high , 5.6 and so I stopped the Spironolactone a week ago. My overnight urine levels have dropped and I have gained some weight. What was really strange on the fourth or fifth night after stopping I developed a huge, very unusual, night sweat with pajamas and sheets very wet. I sleep alone.

Yes it is safe to take the two together,Furosimide is a diuretic to keep the fluid levels down in your system but Spironolactone is a potassium spearing drug. If you have congestive heart failure your system is low on potassium and you need it in order to maintain some form of potassium in your body.

I have taken both for almost 3 years now. Prescribed by my cardio doctor. I looked on my sheets that come with meds niether say anything about the two drugs interacting. There are alot of warnings on everything on websites, best thing to do to rest your concern is talk to your Doctor and Pharmisist. Just my two cents worth

I am also on Spironolactone this medication will cause access potassium in the body.The Furosemide will remove potassium.The Dr. may have added it for that reason. Keep up with your potassium levels,to high or to low can be very dangerous.Both are for access fluids among other illnesses.Both causes the kidneys to get rid of unneeded water and salt from the body into the urine.So you are on one that retains potassium and one that removes potassium. Both remove salt.Hope this helps.

It is fine to use furosemide with spironolactone. There are no known interactions between these medicines. However, this does not necessarily mean no interactions exist so if you experience any odd symptoms please see your doctor.

https://www.drugs.com/interaction/list/