I was told it was a combination of Xanax and Flexeril. I would really like to know because my Dr. recently put me on it.
What are the ingredients in Zanaflex/Tizanidine HCL 4 MG Tablets?
Question posted by Amanda Ricketts on 7 Aug 2012
Last updated on 19 March 2020 by masso
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8 Answers
Major
Tizanidine (Includes Zanaflex) ↔ hypotension
Major Potential Hazard, High plausibility. Applies to: Hypotension, Dehydration
Tizanidine is a centrally-acting alpha-2 adrenergic agonist with 1/10 to 1/50 the potency of clonidine in lowering blood pressure. According to the manufacturer, two-thirds of patients in a study given single 8 mg doses of tizanidine had a 20% reduction in either the diastolic or systolic blood pressure. The effect was seen one hour after dosing and peaked at 2 to 3 hours post-dose. Bradycardia, orthostatic hypotension, lightheadedness, dizziness and, rarely, syncope have occurred. Therapy with tizanidine should be administered cautiously in patients with or predisposed to hypotension. The risk of significant hypotension may be minimized by gradual dosage titration. Patients should be advised not to rise abruptly from a supine position.
SOURCE: https://www.drugs.com/disease-interactions/tizanidine,zanaflex.html
Be extremely careful with this drug. It is very potent. I would first try only 1/2 a pill. Just to make sure it is not too strong. Also a lot of physicians are NOT heeding the interactions with other meds and other reactions with heart ailments. Drugs.com stipulates THIS IS NOT TO BE USED WITH ANTI BIOTIC CIPRO. THIS DRUG IS ALSO NOT TO BE USED IF A PATIENT HAS ANY UNDERLYING HEART DISEASE OR DISORDERS SUCH AS HEART ARRHYTHMIAS ETC. Because muscle relaxer effect your heart muscle’s ability to beat.
Does this medication contain codeine or penicillin
I am not sure
I am currently taking tizanidine hcl/4mg, i take it for muscle spasms and when i get a new medication i always look it up. i agree with the other comments from the others. as far as i know there is not any xanax or flexeril, so don't worry. i take 1/2 to 1 tab 3xs aday. i wouldn't worry.
judi
I have been on Soma for so long it no longer works for me anymore. My doctor just prescribed this drug for me and I am so scared to take something new. Does this drug work well for you? -Thank You Judipe
No. It is not a combination of Xanax and Flexeril. Who told you that? I hope it wasnt your Dr. Xanax is a benzodiazepine and tizanidine is not. Tizanidine is a muscle relaxant. Flexeril is a muscle relaxant too, but flexeril (or cyclobenzeprine) is actually chemically closer to the tricyclic antidepressants. Tizanidine is chemically closer to clonidine which is an antihypertensive drug (for high blood pressure) Clonidine is used for high blood pressure but it also is used by recovering opioid abusers for sleep and to reduce increased blood pressure caused by opioid withdrawals. It also seems to reduce some of the restlessness that comes with opioid withdrawals.
If you need to stop taking tizanidine after taking it for a period of time, it should be tapered to avoid withdrawals or rebound effects. Three cases of rebound symptoms on sudden withdrawal of tizanidine have been reported. The case reports suggest that these patients were also misusing narcotics. Withdrawal symptoms included hypertension, tachycardia, hypertonia, tremor, and anxiety. As with clonidine, withdrawal is expected to be more likely in cases where high doses are used, especially for prolonged periods. Zanaflex Capsules(tizanidine) and Zanaflex (tizanidine) tablets are bioequivalent to each other under fasted conditions (empty stomach), but not under fed conditions. It is best if you start with capsules to stay with capsules and if you start with tablets you should stay with tablets and not use them alternately. The dose can be repeated at 6 to 8 hour intervals, as needed, to a maximum of three doses in 24 hours. The total daily dose should not exceed 36 mg. Hope this helps you to understand tizanidine better!
Where oh where do people get these foolish ideas? Tizanidine is tizanidine, not xanax or flexeril, or anything but tizanidine. When you look up a medication and it gives you the generic name, if it is one med in the pill it says one thing, if its a combo pill as in percocet, it would say oxycodone/tylenol. Drug manufacturers don't sneak other meds in without telling you.
Perhaps in describing how tizanidine works someone could compare it to a cross between cyclobenzeprine (Flexeril) and Xanax but that doesnt mean that they are chemically related in any way.
The active ingredient in Zanaflex is called tizanidine hydrochloride. It is a muscle relaxant and works by blocking pain sensations that are sent to the brain. It does not contain Xanax or Flexeril.
Zanaflex, Flexeril and Xanax can all be used as muscle relaxants but they work in different ways.
https://www.drugs.com/zanaflex.html
Related topics
flexeril, xanax, zanaflex, anxiety, muscle spasm, sciatica, tizanidine
Further information
- Flexeril uses and warnings
- Xanax uses and warnings
- Zanaflex uses and warnings
- Tizanidine uses and warnings
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