I have Psoriatic Arthritis and have been taking Methotrexate since April. I have been suffering with mouth sores like never before. I have been prone to canker sores all of my life but never like this. I have read that taking Methotrexate can cause mouth sores but I do not know if the mouth sores from the medicine would be in the form of canker sores or are the canker sores just from the disease itself. I'm thinking perhaps from my comprimised immune system. These sores are making me insane and often times depressed. They sometimes get so bad that it is difficult for me to even speak let alone eat.
Can any one offer any explanation or help?