I had walking pneumonia at Thanksgiving and was prescribed levaquin. The next day I noticed soreness in calves. The soreness, in three days, developed into tendonitis in ankles and in shoulders. I had no idea that levaquin was causing this and took levaquin for the ten days prescribed. This has now caused me considerable pain and limited my mobility and activities for five months. It seems to be permanent and I am very angry.
I have levaquin-induced tendonitis. Is there anything that will help me?
Question posted by donpat123 on 24 April 2010
Last updated on 14 May 2023 by Dhunt1313
This question has also been asked and answered here: How long does tendonitis last from taking Levaquin?
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39 Answers
The same thing happened to me. I started Physical Therapy 2 months after all the pain and immobility started. I just finished PT after 3 months and I’m at about 85%. I still can’t walk my dog more than half a mile but they think after a year I will fully recover. I can now reach better and do most things pain free. Try PT if you haven’t yet.
I am taking Levaquin for six days already. The first two days it made me very sick. I found out online that you can take vitamin C to avoid tendinitis, and you can take milk thistle to help your liver while under the treatment. I stopped all physical exercise, and I also stopped taking my multivitamins. Levaquin has interactions with many vitamin supplement. I read about Levaquin interactions online. I have to take it for another week, but I’m paying attention to my body. I feel better now, but I feel a little pain in my liver..
Came her for a somewhat positive story. 27 YO male took Levofloxacin for 2 days 500 MG. It destroyed my body. Joints and muscles aching and weak. Tingling down my arms. Right calf and achilles tenderness. Terrible headaches and brain fog. Insomnia, anxiety, everything. It's now been 8 days since I stopped and my body is mostly recovered. My muscles are still weak and my right achilles is going to require more rest, but overall much better. This drug is pure poison and should never be prescribed. Take a different antibiotic unless there's no other option for a serious infection.
In 2016 I was 22 and had pneumonia and I have asthma and my doctor prescribe cipro. On day 6 out of 10 I had Tendonitis in my ankles and wrist so bad I couldn’t move my joints. My doctor said she’s never herd of this and I stopped taking the antibiotics. It took 6-8 weeks to get my motion back with physical therapy. Also CBD oil was the only thing that really helped. But since 2016 I’ve had flare ups about every 6 months in my wrist or ankle. Then I just ware braces and take extra CBD oil. Now this flare up is in my ankle and had an MRI and now I need surgery. So from experience the more I work or exercise a lot it flares up. Also I have EDS which is a genetic cartilage/ collagen disorder. So if you want help with the inflammation and go through every day life without pain, I would suggest CBD oil, but make sure it’s Pure and not any added ingredients. I’m glad I’m not the only one who’s going through this.
Has anyone who commented gotten better?
Hi, I first had the problems in January 2017.. Unable to walk for 3 months, and pain in my right arm.. I was back at work after the 3 months with some soreness.. Its now August 2019 and have been pretty good.. Occasionally get twinges in my left ankle.. Last summer 2018 I developed soreness in both forearms, I believed it to be from eating pork meatballs that possibly contained the drug, I actually went vegetarian for just under a year.. Back now on meat for the last few months with no change.. My arms aren't bad now just sore from time to time.. I spoke to others when I was on a bad way on Facebook.. People literally confined to a chair with all over skin pain.. One guys wife left him due to it all.. Sold all his belongings to keep his house.. Last time I spoke to him he's back at work and doing really well.. You can get better from this.. Try and stay positive.. All the best
What are the doctor's doing to help people with this. Did doctors help anyone?
My doctor agreed it was the drug that had caused my problems.. Said its very rare and unfortunate.. I went back a few months ago with prostate pain and another doc said "I better give you some antibiotics just to be safe" . I said "it's not cipro is it?" he looked at me and said "yes, why?" I told him what had happened and said he'd had one other patient in all the years he'd been there.. I'm sure that's not true though.. All the docs I saw told me to use nsaid creams.. I would avoid if they offer you this as it can cause more problems.. Theres some good Facebook groups, people on there are very knowledgeable about the problem..
I found a law firm on the internet today that said they represent cases for Levaquin cases. I filled out their form, and immediately got a reply that stated they did not want to take the case. So, apparently it is very difficult to win against the big drug companies... This is so very, very sad. Because most people do not even realize it is the drug hurting them. And, they do not report it to anyone. I do not think this is rare at all. Because I happened to mention it to a friend of mine. He happened to have just been given the drug, and we compared notes. He is having horrible problems since taking it too. What is t the e name of Facebook groups?
Wow, sorry to hear friend could be having problems too.. I'm in the UK so may be a little different, I'm guessing you're in USA maybe as I don't think they have levaquin here, just ciprofloxacin.. I found others in a UK group, quinolone toxicity support uk.. There are some other groups also.. I think I remember someone telling me once the American group had something like 250 or so people a week asking to join.. I may be wrong on that but I don't think its a rare as docs make out.. Jut search Facebook for quinolones or cipro and should find the groups.. Hope it is of use to you
Thank you. If you have any other information on what you tried, like becoming a vegetarian for a year, let me know. Yes, my friend and I are in US. They prescribe Cipro here too.
From talking to other people one of the issues is magnesium depletion.. So I was trying to eat foods that were were rich in magnesium.. Things like spinach and kale.. I bought a magnesium cream and an oil from amazon and applied it daily to my ankles and arms.. Also occasionally had a bath in Epsom salts, which is good for aches and pains generally.. Also I got some magnesium supplements.. Unsure which is the best type for you. I had magnesium citrate which I don't think is one of the better ones.. Google should help.. I didn't overdo it though.. I think being sensible and just time we're the main healers for me.. Also worth mentioning again.. Everyone that new most about this said to avoid nsaids.. Ibuprofen and anti inflammatories.. Some people say it worsens the problem.. Happy to talk if I can help in any way..
It's been 8 days since I stopped and my body is 90% recovered. Right achilles is going to take a while. I wish I had seen more positive stories during the dark days...
Dear Donpat123,
I am very angry at my very recent painful side effects from Levofloxacin/Levaquin too. Am freaking out about all my pain, and weird pains in strange places. I took a ten day dose beginning July 23, 2019. No doctor or pharmacist mentioned a word to me about how dangerous it could be. No one asked me my health history or even what drugs I was already taking. I am 67, and totally terrified. Someone mentioned a class action lawsuit. But, not who to contact. This drug should be banned!!!
I was given Levoflaxacin for pneumonia in February 2018. After taking seven doses, I literally could not move the following morning. Tendonitis hit every joint and muscle. Physician said I had tendonitis, apparently induced by Levoflaxacin. I was never warned about the side effects from physician or pharmacist. Physician gave several rounds of steroids, which helped. Still had terrific pain in left leg and right wrist. I have been taking CBD oil dailey since June 2018. Still have a little pain, but could not make it without the DBD oil (1/2 vial of 1500mg each morning). Truly, I believe I will have the tendonitis forever. I warn everyone I know a bout the Levaquin drugs. Personally, I think it should be taken off the market, but money talks; and supposedly it does help some people. Many of us are allergic though and are in pain from it.
I am allergic to almost every antibiotic there is ranging from anaphalactic shock to hives head to toe. Only a couple make me sick as a dog the minute it goes in I feel ill and within 15-20 minutes I am in the bathroom throwing up projectile style until everything that day is completely gone. I recently went to the ER and when they checked my blood work my potassium was 2.1 and my white cell count was 23. They admitted me and because my numbers refused to stay steady they kept me for 5 days. The diagnosis was Pneumonia. I was pumped full of Levaquin IV bags if I counted correctly there was 7 or 8 bags hung as well as potassium and something else. Because I have a tendency to fall they did not want me up walking around except bathroom runs. When I was released they gave me 3 - 750mg Levaquin pills and I noticed the back of one leg and both ankles hurt when I walked.
I had an appt with my Ortho doc and asked him why the back of my ankles and calf just below the knee were hurting so much. He asked what they gave me in the hospital and he said yep it was most likely the Levaquin. Yesterday I had to go to the ER because I went to step over something and fell on my right knee and hit my head. I now have 14 staples in the knee and my left ankle hurts so bad it makes me want to scream. I was told not to overuse. This med since the Dr did not want me becoming tolerant since I have so many antibiotic allergies. Now we have this problem. I am unsure what they can really do when I am sick.
I have Tendinitis from Levaquin. Have been doing PT after cortisone shots. PT seems to be agitating more than helping. Has it helped anyone else?
I suffered from this many years ago after being prescribed levaquin for a persistent case can of bronchitis.
My wife suggested I go to a homeopathic doctor. I was very much sceptical of homeopathic medicine, but felt I had nothing to lose. I was given a remedy and much to my surprise the tendonitis pain stopped within a few hours and never returned. I don't recall the name of the remedy but if anyone is suffering from it I would suggest giving it a try as you have very little to lose and much to gain.
It worries me all the comments about needing supplements and so on. Unless you have a very restricted diet, the average American diet is full of everything you need and more. No evidence that anybody’s deficit in anything, and not magnesium – unless you’re a chronic alcoholic who drinks instead of eats. Taking these mega-supplements of other stuff can be harmful. The body can take a lot, and will throw off any excess usually, but it’s a waste of money too. And herbalists and “naturopaths” are not Doctors. Nowhere remotely close to the training in medicine a doctor gets-though they don’t often listen, nor does everything have an answer-though “natural medicine” fans will say they do. Anti-inflammatories can be tried – they don’t make anything worse-it would just be for Pain, but the pain is likely more on a neurologic basis than inflammatory basis, So they’re not going to fix it.
@Doctor555, I disagree! If Americans truly get enough vitamins and minerals from all the food we eat, we wouldn’t be low on vitamins such as D, magnesium, etc. I am living proof with all the supplements I took it helped me to overcome the fluoroquinolone toxicity I suffered from. The problem is doctors are not taking the time to read the black box warning stating that fluoroquinolones should only be used as a last resort and not a first line of defense to every day common infections such as sinus infections, UTI’s, etc. Furthermore, the use of steroids or anti-inflammatories only exacerbate the symptoms. I couldn’t understand why when I took ibuprofen, my pain increased in my joints to the point of barely being able to walk. Then I came across information that explained that anti-inflammatories should be avoided. Once I stopped the pain lessened and I worked on building my supplemental attack of the toxicity.
Over time (a period of 6 months) it has become tolerable and manageable. Knowledge is power! While I respect the education of doctors, I will always do my own research on prescription drugs now and will discuss options with my physician if I deem necessary for my own health.
Magnesium levels are easily checked in the blood. And the symptoms of true magnesium deficiency are much different. Vitamin D level range is spurious. There’s a lot of talk in the medical literature to revise the “normal” range. The testing on how that range came about was flawed. I’ve practiced in California and Florida for 30 years it’s rare that I get a normal vitamin D level on people—who have lived in the sun all their lives. It’s just wrong.
What source did you read that said anti-inflammatories are bad for this? There’s a source and then there’s is a source. Lots of garbage in the Internet. No offense, but without the medical background and training to interpret this information (like 8-10 yrs of training) you really will not be able to have a grasp on the whole picture. And you are a case of one. Once you’ve treated hundreds of these patients, you have a better idea of what’s real and what’s coincidental.
I trained in Boston, and occasionally we would see a bonafide vitamin D deficiency patient. It was almost always in the winter time (short days, little sun ) in a shut-in person with a poor diet. A lot of elderly women live on tea and toast, and don’t consume dairy. That, combined with the lack of sun, can cause vitamin D deficiencies. They will university have osteoporosis as well. Very occasionally, someone with extensive get resection may not be able to absorb vitamins – but that’s mostly at the B vitamins, and very advanced kidney disease can do it. Reading sites like Webmd will not give you trustworthy information. But lay persons don’t have the background or vocabulary to be able to read the scientific literature. That’s why you need a good doctor. It’s not just a matter of gaining information – it has to be legitimate information, that you can comprehend, interpret, and apply—because you have the background and training to do that.
Google doesn’t cut it
First of all, I am so sorry to hear you are experiencing side effects of Levaquin. Like with all side effects, it affects people differently. I spent many months with knee and joint pain and lots of money on various supplements. There is a lot of support groups online and advice on what helps, what doesn’t. I am limited to what I can say or recommend on here so getting in touch with a group is what helped me. It is possible to recover and I have improved greatly if that is any encouragement to you. I found my help on social media (Facebook has many fluoroquinolone support groups which is the drug class of Levaquin)along with lots of research of my own. Just remember getting advice from support groups should also be combined with your own knowledge of your own health and research from reputable sites. I can honestly say any drugs I take now is researched on effects and I prefer vitamin/mineral/herbal supplimentation over any prescription drug. Good luck to you and hope you find relief soon from your tendinitis pain.
DHEA 50mg , turmeric 4 pills per day , magnesium 750mg , potassium chloride 1500mg (or isopure protein powder if you can't get potassium pills, it has a LOT) , choline 500mg , protein powder 60g , massage therapy once per month, ice ... Pray ..
No more Prednisone !!! Ever !!! It breaks down muscle ... Just ask your doctor ...
I took Levoflaxacin in January 2018. After seven days every joint and muscle ached; could not sleep. Now after two rounds of prednisone, I am better. However, I still have substantial pan in the left calf, right shoulder and right wrist. Three days ago I started cannibus oil. I will report the results in about two months.
I am so sorry to hear you have had this issue. I also had a reaction to Levaquin. Like you, started in my calves, but over several weeks, I was so swollen all over from the inflammation. At the worst, I couldn't fit in my shoes, wear my wedding rings, grasp anything (like pulling up covers in bed was not possible), and couldn't wash my hair by myself.
I can only tell you my journey, and what my Rheumatologist and I did to help me.
After attempting multiple different anti-inflammatories, and pills for rheumatoid arthritis, none of which worked, we made the leap to steroids. My dosing for effect was luckily small, usually 5-10 mg daily. Prior to my first pregnancy, I was started on Humira, and it was a MIRACLE!!! absolutely zero pain for the first time in months. I stayed on that for 6 months, but had to go off to get pregnant. Once that was out of my system, the pain and swelling returned with a vengeance.
So, I went back on steroids, and I was on this for 6 years (until done w kids). After kids, I went back on Humira, but it didn't work this time around. So, after several months of taking Humira and steroids, I switched to Enbrel, and it has been great for 2-3 years.
Hopefully you can meet with a good rheum that knows the literature, and is willing to help. The first doc I saw was extremely dismissive. I am a physician myself, and knew what I was talking about. I knew there was something wrong. Luckily, I found the right doc, and I have been extremely functional since. I have had several small tendon issues since, but nothing I have needed surgery for. Good luck. Hope this helps!
Related topics
Further information
- Levaquin uses and safety info
- Levaquin prescribing info & package insert (for Health Professionals)
- Side effects of Levaquin (detailed)
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