How long does it take to get rid of a middle ear infection?

Unless it is a major infection and the doctor ordered 2 meds, you shouldn't need 2 meds. You should have some relief by day 3 of the meds, although it might not be total relief.Watch for symptoms of yeast infection and you can treat with the miconazole bullets during the course of antibiotics. If you are on the pill, make sure you use a back up method, especially if you do take both of the antibiotics.