I have been treated for depression for over 20yrs and now have severe major depression for last 6 months. I take 150 mg Effexor XR and it doesn't seem to be working. I also have anxiety and panic attacks.
Sorry you are having so much trouble finding an anti-depressant that works for you. I am bipolar type 2 depressed, which means I hardly ever get manic. So, essentially I have been depressed most of my life.
After pooping out on SSRI and SNRI meds, my shrink tried me on Lamictal along with my trusted old friend Klonopin. I started with a dose of 25 mg a day and maxed out at 200 mg daily. After a couple of weeks, started feeling a whole lot better. It was amazing to me. So I'm just giving you my extensive experience with anti-depressant meds, 43 years worth, the Lamictal was the answer to my prayers.
I recommend Pristiq which is an improved version of Effexor. Also, you have the option of increasing the Effexor XR to a maximum of 225mg. I have had to change my antidepressant every 5 years or so to get continued relief. I am finding Pristiq to be very effective.
Hi,sorry 2 read u have had it that long. Efexor 75mg,in the past helped me with depression,i get down at times,i önly now take valium2 relax my mind n body,and also take a stress free natural herb tablet,anti depresants dnt always wk,but we r all different,talk 2 a doc c wat else they recommend.my pschlgst 4 my anxiety a big help ,im doing gym,piltates relaxes me beta than a tablet,do u keep urself busy?i hope u find an answer 2 feel better.
There are so many, and so many variables as well. What works for one does nothing for someone else. All I can offer is you stay in touch with your Dr and hopefully/eventually you'll hit on something that works for you. Be patient (no pun intended) and keep a good relationship with your Dr. Hope this helps.
Did your Effexor ever work? Pristiq is similar to Effexor, so the change from Effexor to Pristiq should not cause major withdrawal symptoms. I didn't feel much side effects from the change. I changed to the Pristiq to get a better sex drive which it did help.
Well, I liked Cymbalta and I was dealing with Recurrent Major Depression with Suicidal Ideation. Two medications in my entire life have ever worked for me on that issue. The first was PARNATE an MAOInhibitor which I was on for 8 years until it seemed to stop working. The second was Cymbalta which worked quickly for me and was on up to 120mg then dropped down to 60mg. The starting dose is 30mg.
It is also possible that you may need a combination of medications: one to handle the depression and the second to handle the anxiety.
For the anxiety and to help me sleep, I take Ativan 2mg at night.
I hope that helps you and gives you some food for thought. Good luck with it and keep us posted should you need additional support or still have questions.
It appears that u feel the same way that I feel. If u have been battling depression for 20 yrs, have u tried several ADs? If so, which ones have u tried? I recommend that u add SAM-e to your AD as soon as u can. Of course after u talk it over with your dr first. Also, if u tried most of the newer ADs then perhaps u should try the older ones, MAOIs, etc. Have u tried prozac, wellbutrin as an add-on, Paxil, Cymbalta as an add-on, SAM-e as an add on, or deplin as an add-on, inositol as an add-on, celexa or any of the popular ones that pop-up when we google medication for depression?
I recommend that u research all the ones I mention above & take the list of the ones u wanna try to your doctor. If u don't have any get up & go or if u isolate today, then u do indeed need to change meds & the sooner the better, but if u change & feel that the 4-6 week wait is taking 2 long for you, u should consider adding the SAM-e soon as possible. U can buy it from Vitacost website or Swanson's vitamin website pretty cheap. Please, please keep me posted & hang in there! God bless u!
Cymbalta worked great for me for anxiety and panic attacks. After about 3-5 days I noticed a huge difference. I don't have severe depression & wasn't on it long enough to respond to that part of it. Hope you find something that works for you. Kim.
Hello PNHHM2. Given the length of time you have been suffering, I suggest you go the route of a MAOI such as Parnate. Regards, pledge
You have had lots of answers & suggestions here, but personally I feel that everyone reacts differently to different drugs. Your best bet is to discuss this with your psychiatrist if you ave one, & tell him/her exactly what you have describe here. Sometimes we get accustomed to a medication & need an increase of the dose, or they may add a different one. With depression meds, it can be a trail & error type of thing to find the right combo that helps you. My husbby is bipoar & takes zoloft. It worked quite well for a number of years, but then they added wellbutrin with it & he has had wonderful relief. It is best to let your doctor decide what will work for you. I wish you the best...
I find it's trial an error with anti depressants. Effexor didn't do much for me either. It took a long time before we found something that worked for me. Manerix with Lithium is what finally worked for me. I find there is always restriction with all drugs so just need to adapt that all. If it works it's really worth it! I no longer have depressions now.
Good luck and take care!
Hi, I have Bipolar 2 which the last person mentioned as well, and I too have had amazing results with Lamictal added to Wellbutrin, and Zoloft. I also have anxiety issues so that why I take both antidepressants.Although for many years Wellbutrin somewhat helped my depression by itself,it was not enough, & that when I was finally diagnosed Bipolar 2. I have had to adjust doses a little bit here and there, but overall I have felt good. I sincerely hope you can find relief, I know how hard it can be just to function at a minimal level..I would keep trying different drugs but most importantly, make sure both you & your Psych/Counselor is really communicating well, otherwise find another one that you "click" with.. Remember, they are supposed to work with you and for you, not treat you like just another number.. JT
Hi PNHHM -
Since we haven't heard back from you in a while, I am just writing to see if you are okay. I hope that some of the suggestions that we gave you have helped and that you have discussed all possibilities with your psychiatrist. I hope you have a good psychiatrist or psychopharmacologist and not a GP. When it comes to matters of the "head"; the best resource is one who really understands the medication and mental health issues.
I wish you well and much enlightenment on your journey.
Thanks. I would like to participate
Hi there your definitely not alone I would try Cymbalta w/ Xanax. Try Depakote first its a mood stabilizer and helps level out alot of issues. Best of luck.
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