Fluorouracil - When does irritation start and can it be covered with makeup during treatment?

Fluorouracil is a topical cream that used for treatment of pre-cancers called actinic keratosis. It is used for 2-6 weeks depending on the area being treated. Most patients use the cream twice a day for 4 weeks from start to finish. The treated areas may begin to get itchy, red, irritated, or sensitive by 10-14 days. Once you finish the full 4 week treatment, the areas calm down over the next 1-3 weeks. Many are able to use make-up over the cream, but it can sometimes sting.
https://www.drugs.com/comments/fluorouracil-topical/efudex.html

I just started my treatment today and am anxious about it. I was glad to see your question and the reply. How did you make out with everything?

How did your treatment turn out? Curious bc I have started mine this week and looking for some feedback as to how it all worked out and if you think it was worth it to use the cream

I only had to do between my upper lip and nose. It started to get a bit red near my nose after a week and at first just looked like I had a cold. After about 1.5 weeks it was much more irritable-looking. It scabbed over very quickly too so it was impossible for me to use make-up. I simply used vaseline or aquaphor 2x per day about 2 hours after I would use the cream. About 3 weeks in I tried my normal Neutrogena moitsturizer with SPF on it and that burned horribly. I made it the full 4 weeks and am now about 4 days post and it looks much worse. You know when a sore heals and it looks worse before it gets better? I am in that phase.