Does vagifem disolve immedialtely in vagina?

This is what has been reported on Vagifem: After inserting the filled applicator, gently press the plunger until you hear a click and the plunger is fully depressed. This will eject the tablet inside your vagina. The tablet will dissolve slowly over several hours.

Read more: https://www.drugs.com/vagifem.html#ixzz0psAmDTi0

However you could speak to your gynecologist for more details, hope this helps?