This question has also been asked and answered here: How long does Methadone stay in your system?
Methadone is a really strange drug that effects everyone who takes it differently, thus the reason why you're probably asking this question cause there's no good answer. The longer that you take the drug, the more of the drug there is that builds up in your liver (it however doesn't harm the liver, just hangs out there). So... when you take it for the first week, the drug would be out of your system anywhere from 8 to 50 hours (according to one source). If you've taken the medication for a long time, then the clearance rate will of course be much much slower. Also, this is the same reason as to why there is no good conversion rate from methadone to anything else, it simply varies too much. I know that there are some sources that will quote a conversion, but these are never very accurate, and are really nothing more than a loose guess if it converts for long term usage. Hope that this is of some help!
i asked my doc the same question, and that is one of the biggest debates right now, it really depends on multible factors, how long, how high of a dose, your metabolism, they are not even sure of the half life of methadone it is different for everyone. sorry we couldn't give you a more direct answer but there isn't one.
- Methadone Information for Consumers
- Methadone Information for Healthcare Professionals (includes dosage details)
- Side Effects of Methadone (detailed)
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