I took Omeprazole (generic for Prilosec) for 12 years when I found that I was having some horrible side affects such as Urinary Tract Infections, Sinus Infections, bone pain, shortness of breath, nausea in the morning, etc. I slowly stopped taking the above and am now on Zantac #150 each morning an hour before my meal. I tried taking a second one since heartburn returns after 8 or 9 hours of taking the Zantac. I noticed some of the symptoms return that I had when taking the Omeprazole such as the shortness of breath. Is there a difference between the Zantac and the Omeprazole and what is the difference?