Fundamentally they differ only in that desloratadine (decarboxyethoxyloratadine) is the major and more active metabolite of loratadine. Desloratadine have a very longer half life, approximately 24 to 27 hrs, than loratadine (aprox 8 hrs). Both are h1 receptor antagonists antihistamines, but desloratadine is moderately more effective and very long acting.
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If an extra dose of loratadine was administered by mistake i.e 10mls of syrup taken at 8am and again
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Is there any additional benifits of desloratidine over loratidine?!! especially in syrups for child?
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