Is there a difference between 2 500mg Metformin and 1 1000mg Metformin Hydrochloride?

I think no difference

Iamnot sure I only know that my Doctor wants me to take 2 per day.

Well I am a diabetic type 2 and that is the medication I take. Its been almost 8 months now. It could be a huge difference. Only take what your Doctor has prescribed you. I take one 500mg two times a day which totals 1000mg. But my body needs the 500 spread out over 2 a day. If this is prescribed you then it should say on your bottle what you should do. My pills by the way do not have the hydrochloride on the bottle so that may even be a different medication than just the metformin. All that information is here though... check it out.

The only difference I can think of is you'd be taking more pills at a time with one of them. Sometimes doctors and pharmacist alike are hesitant to have a person take a smaller dose pill, but take 2 of them, for fear they won't understand and take only one. I figure as long as you're of average intelligence you can figure it out, lol.