the 500mg ER formulation is extended release. This reduces the stomach upset associated with the drug. However, it also is a bit pricier and not preferred by physicians. The 500mg IR (immediate release) is a fairly standard dose that can be tapered up simply by changing the dosing around. The ER tablet does not have this luxury.
- Metformin Information for Consumers
- Metformin Information for Healthcare Professionals (includes dosage details)
- Side Effects of Metformin (detailed)
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