Depression - New to Pristiq - Very tired and has a powerful effect on me?

Hello, I see this an older post but wanted to say I also have been on Prozac, effexor, several others that I can't recall. Some did ok, others not but seemed I had side effects of some sort with all of them. I recently done a DNA testing thing from Doc that is supposed to help dial in the right one for you. It showed 50 mg Prestique was right for my body. I took for a while, maybe a month or so, and quit cause I had a lil funny feeling in my head and tightness in my jaws that was aggravating. My mood got much worse after quitting and decided to go back on. It does make me extremely sleepy as well so I'm going to do the night dose but does seem to carry over to next day. If it's going to help my mood and extreme irritability then I guess I'll just be tired. Doc says this is what I need. Who knows.

No, you cannot cut the Pristiq up or will not work properly. I checked with my pharmacist about it. I take mine at night which would make more sense for you if it makes you sleepy. Pristiq is the upgraded Effexor which you can take in far lower doses. I would ask for Effexor instead. Some people do have difficulty getting off of Effexor and probably Pristiq, but my friends have reported no problems going off of it twice. I have gone off of if gradually twice without any problems. That is GRADUALLY. Both the Effexor and Pristiq have been truly miracle drugs for me. Millions of people take them. But if you continue to be so zombie like, then you need to take either the smaller dose of Effexor or a different anti-depressant. Good luck. And let me know how it goes for you.