I had taken the Depo shot, I got bloated, cramps, acne on my shoulders, back and some on my face. I lost my sex-drive. I began to question my relationship and wonder if it's what I really want, been more irritated at work. I have switched to the BC pills from before the shot (Tri-lo-Marzia). I am on my 4th month of the pills. Also my cramps this month was bad the first day of my period. I have never had cramps with the pills before either. If I did, it might have lasted a few minutes. I used to have sex with my BF 2-3 times a week before the pill. I really need my sex-drive back!!