Are they prescribed for different medical conditions? Do the pills contain different chemicals? Which of them causes the least side effects?
Wellbutrin - immediate release pills taken three times daily for the treatment of major depressive disorder.
Wellbutrin SR - sustained-release pills taken twice daily for the treatment of major depressive disorder.
Wellbutrin XL - extended-release pills taken once daily for the treatment of major depressive disorder and seasonal affective disorder.
All Wellbutrin formulations contain the same active ingredient, bupropion.
Sorry I couldn't find any information comparing the side effect profiles for each of the types of Wellbutrin. In general the longer acting medicines have fewer side effects because the blood levels of the drug remain steadier.
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