I have been on Zoloft for 5+ years. I started to feel like it was not working. Not sure if it was the dark long winter days or just that I built up a tolerance. My Dr increased my dose from 50 to 75 mg. Day 1-6 no noticeable change but the last 5 days I have been anxious, shakey and not sleeping great. I feel like I should just drop back to the 50?? I can't imagine going another week feeling this way. Today is day 12. Any advice on how to relax? Or do I just have to tough it out.