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Can you take Tramadol along side Valium ?

8 Answers

ocean19 11 Oct 2017

My doctor put me on it and two pharmacists told my husband that it was a dangerous combination, one of the pharmacies actually called the Head Pharmacist out to talk to hubby, they were quite concerned. I was on three 5mg valium and 300 mg of tramadol.
So I told my doctor (very nicely) what they said and he got so mad and said then let them prescribe your medications, walked out and was done with me.

Got a new doctor, the first thing he did was took me off the tramadol, I have to have the valium for a neurological condition. He said this combo can cause blood clots and is a bad combo especially if you have high blood pressure or are a senior. I am on BP meds. I said it doesn't really help the pain much but it helps me sleep. He said that's showing a problem, the combo is shutting you down.

Just my experience but I thought it was worth sharing.

Votes: +0
klsnyder101 1 Sep 2017

Interactions between your selected drugs
diazepam ↔ tramadol
Applies to:Valium (diazepam) and tramadol
Using narcotic pain or cough medications together with other medications that also cause central nervous system depression can lead to serious side effects including respiratory distress, coma, and even death. Talk to your doctor if you have any questions or concerns. Your doctor may be able to prescribe alternatives that do not interact, or you may need a dose adjustment or more frequent monitoring to safely use both medications. Do not drink alcohol or self-medicate with these medications without your doctor's approval, and do not exceed the doses or frequency and duration of use prescribed by your doctor. Also, you should avoid driving or operating hazardous machinery until you know how these medications affect you. It is important to tell your doctor about all other medications you use, including vitamins and herbs. Do not stop using any medications without first talking to your doctor.

Votes: +1
midnightdr3ary 24 May 2017

Something no one seems to have mentioned thus far is that Tramadol runs a high risk of seizures (even at taken with exactly the recommended dose). Valium can help to counteract the seizure risk, but I would strongly suggest looking into to an anticonvulsant while taking Tramadol. Some, such as something like carbamazepine can decrease the effectiveness of Tramadol, but I think it's worth it over seizing.

Votes: +0
taurusbull 19 Dec 2016


Votes: +0
Delila 9 Aug 2015

I just wanted to add that a friend of mine used to take Diazepam and Tramadol and it made his anxiety worse and made him feel very sleepy/not so in touch with reality...

Votes: +0
Inactive 10 March 2011

Hi Brooke Emery I would not do this personally because some strong drugs like these can conflict with eachother also cause added side effects.If you are having problems with pain management then I suggest you see a pain managament specialist that will help you to work with your pain because what you want to do mix drugs like these is asking for problems. Hope you get this problem with pain sorted out ! take care Candypq

Votes: +1
LaurieShay 10 March 2011

Hey Brooke,

Just to give you the most accurate in depth answer, this is what I found on the interactions checker:

Interactions between your selected drugs
diazepam ↔ tramadol
Applies to: Valium (diazepam), tramadol

MONITOR: Central nervous system- and/or respiratory-depressant effects may be additively or synergistically increased in patients taking multiple drugs that cause these effects, especially in elderly or debilitated patients.

MANAGEMENT: During concomitant use of these drugs, patients should be monitored for potentially excessive or prolonged CNS and respiratory depression. Ambulatory patients should be counseled to avoid hazardous activities requiring mental alertness and motor coordination until they know how these agents affect them, and to notify their physician if they experience excessive or prolonged CNS effects that interfere with their normal activities.


As long as you take as prescribed, you should be fine. Did the same doctor prescibe them both? If not you may want to call one or the other and confirm your dosage of each medication with him/her.

Hope this helped,


Votes: +3
oxyaaron 10 March 2011

Yes it can make you sleepy but i think you will be fine if you keep it in order. i take klonopin, tramadol, vicodin and many others and im fine so you should be too.

Votes: +4
christineATU 10 March 2011

Hope you finally got all the right meds in order. Sounds like you have a decent doctor now. That's good!

caringsonbj 10 March 2011

with medications like these they carry the potential for you to become sleepy but other than that you should be fine, be sure that you do not consume other medication with these or alcohol without consulting your doctor, when taking these two medications be careful when getting up and down and driving just until you are sure of how it affects you. Be safe and take good care

bellarose318 23 Oct 2014

Thanks so much for your answer yall. Are so helpful i wont take anything with out asking yalls opion first free discount card

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