I have taken Tramadol for years off and on. It helps sometimes but not all the time. Celebrex helps my Osteoarthritis WHEN I can get it. I am usually given Meloxicam but that does not work as well.
Celebrex is a COX 2 inhibitor which works differently than each Cox 2 drug. Each one has a different chemical breakdown and although the language is very technical some research into learning the properties of each of these class of drugs was worth it for me. It has been a while since I have done research so I can't explain the technical angle of Celebrex but read as much information you can obtain from each COX 2 drug and you will notice a difference. Stick with what works. Good luck. PS I do not take Tramadol and Celebrex together.
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