BuSpar - How much time do you allow between twice daily doses?

Hi, jammark!
I also take buspirone... 30mg at 6am and 30mg at 8:00pm. I've never changed my dosage except initially when my doses were increased and this timing has worked well for me for many years.
Generally speaking, you should allow at least 8 hours between doses of most medications.
You'll need to see how you respond to the buspirone and experiment a little with the timing because every person may react differently than the next.

Due to the extremely short half life, I initially took at 8 am and 8pm. But that didn’t seem to work as well as I would’ve liked. I still had a lot of “breakthrough anxiety”. When I changed to 8am, 4pm, and 12am, it was like a switch was flipped and my anxiety was shut off. I’ve been on 45 mgs a day since 2002, and it works great for me. I hope this helps, good luck to you.