My understanding is that Wellbutrin (bupropion) works only if one takes it consistently. Does anyone use it sporadically, more like based on what you feel like that day? My husband gets prescriptions for a daily dose of 450mg, but doesn't take it on regular basis. I don't know why his doctor prescribed it to him, as he doesn't have any evident condition typically associated with the med. He may stay on the med for a few days to a few weeks but then stop taking it, or he might take an irregular dose. Could his moody outbursts be due to the inconsistent use of the medication? There are times he just seems "hormonal." I don't know how they correlate with his meds. Just wondering if anyone could share their experience getting on and off of bupropion.