I wanted to see if anyone has some insight on adding Wellbutrin to Zoloft. I’ve heard mostly good things about this.
I’ll start off by saying that I’ve been on Zoloft for exactly 3 years, and last spring (2018) I decided to titrate down from my maintanence dose of 150mg, to 100mg, to 75mg, then to 50mg over the course of about 8 months. In mid-December I had a recurrent episode of anxiety and depression and had to go back up to 75mg, which didn’t quite cut it, then back to 100mg, which I believe I have been at now for about 6 weeks. Going back to 100mg (where I was totally good at when I was titrating down) has not quite gotten me back to where I need to be. The doctor diagnosed me as being in partial remission, and that was two weeks ago, I feel better now than I did then. I may also have to give the Zoloft some more time to reach efficacy again. I don’t want to go higher than 100mg again because the reason I starting titrating down was to lose weight. Weigh gain was the only long term side effect suffered, thank God. Other than that, Zoloft has been great. But again, I’m not where I need to be yet.
Today the doctor prescribed 150mg of Wellbutrin XL to augment the Zoloft, and I’m starting that in the morning when I wake up. This is so I can maybe come off the Zoloft in the future, or greatly reduce it at least, and to counteract that weight gain side effect. I’ve heard that these two drugs play well together and that Wellbutrin can help Zoloft (and other SSRIs) do its job better. Does anyone have any insight on this and can anyone give me an idea of what to expect? I appreciate it.