I have been on Wellbutrin XL 300 mg for many years for depression /GAD. I was recently prescribed metoprolol succinate ER 25 mg to hopefully calm my system down and decrease the physical effects of my GAD, elevated heart rate and elevated blood pressure. There is an interaction that popped up between these meds. Just curious if anyone else takes these 2 meds or has advice. I thought I would start taking them further apart from each other, but I didn’t know if it mattered.
25mg is a very low dose of metoprolol and probably won't be a problem with your Wellbutrin. I take a low dose of a similar beta-blocker, atenolol, along with my bupropion (Wellbutrin) and have never had any problem (low blood pressure or hypotension, etc.) with the combination.
Your doctor is likely aware of this potential interaction but you should probably talk with her/him about your concern.
PS, Wellbutrin has a long half life and it would take a few days for it to be completely out of your system so it may not matter when you take the two of them.
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