My husband developed rash when he was on Pradaxa. It went away as soon as he stopped. He has now been on Xarelto 20Mg about three weeks and the similar rash has started. His back is full of small red spots that itch and his upper chest front seems red and itchy. Could this go away with time or will it just get worse as it was the case of Pradaxa?
Has anyone experienced skin rash while taking Xarelto?
Question posted by wife of TJ on 20 April 2012
Last updated on 19 May 2020 by beautymonster85
I just started Xarelto and have almost like a heat rash on both my back and neck. So awful! They need to put me back on Pradaxa which has an antidote!
I was diagnosed with DVT and PE in Nov 2019. Been on Xarelto since. Initial weeks I had no problem with the twice daily 15mg doses.
I went on vacation at the same time as switching to 20mg single tablet. This is when it started to cause problems.
My legs and then arms, back, lower stomach, neck and buttocks started to develop red patches that were really itchy.
My DVT leg swelled with calf as wide as my thigh. I went to A&E and was given Warfarin injections for 6 days and Benadryl. The leg went down but the itching got worse. I was literally scratching my skin raw.
Back in the UK and saw a dermatologist and haematologist. Had a 5mm skin biopsy and results came back with skin eruption due to drugs. I was given Loratadine anti-histamine, betnovate and ecolon creams (not sure if spelling of drugs is correct) The rash and itching eased with the Loratadine. I stopped both steroid creams as they were drying my skin and it was ageing really fast with wrinkles.
No was skin is better but skill feels like I have insects crawling occasionally under my skin. Take Loratadine with Xarelto and food.
Had further blood tests and discovered high antibodies in blood so having further haematology consultations to explore CREST and Lupus as my DVT was unprovoked.
My experience is you have to be persistent to get the tests needed!
Good luck all!
I have been on xarelto for one week and have developed skin rash on back and severe itching been to er twice in one week same answers its not due to the blood thinner they say its uncommon for that to happen they saying its a reaction to the tape that im using on my back from my back surgery. Wont switch my blood thinners. Asked to go on heparin they told me they wont admits me in hospital to start that. Im aggravated upset and at my wits end. Any suggestions. Ty fed up.
I have been on xarelto for over 5 years and have tolerated it well. Started at 20mg/day for dvt prevention and am now on 10mg/day. Several weeks ago I had facial blue light phototherapy at a skin cancer center and several days later broke out with a severe itch on my back with red pustules developing. Returned to the dermatologist and was instructed to take benadryl and a 2.5% prescription hydrocortisone topical ointment. This did not alleviate the itching which is worse at night affecting my sleep. I am wondering if the light treatment somehow reacted with xarelto to cause this itching.
I developed a rash , red, itchy on my back after starting Eliquis. I was changed to Xarelto and the condition worsened and spread. I was put on Coumadin which caused an immediate intensification. I stopped taking all drugs, except baby aspirin, over a month ago. I still have the itching rash, front and back, from ears to ankles. I have applied every cream and ointment on the shelf at Walgreens. Saran with menthol helps a little, temporarily . I also try bathes with colloidal oatmeal, for similar temporary relief. Anyone have any better answers? Any better idea of a timeline to cure?
My Dr put me on Xarelto for atrial fibrillation. After about 2 weeks I began to see red burning itchy spots all over my body. About 3 days later I wound up at urgent care with a severe reaction. Including swelling of my throat and face and problems breathing. After a shot and 14 days of 40mg per day of steroids the rash finally dried up. It left some permanent scarring on my arms and back. Now the Dr wants me to try Predaxa to see if it will work but I'm scared to death to try it since my pharmacist told me if I was allergic to one I would probably have the same results with all of them.
My elderly mother had been prescribed Xarelto in the past for the treatment of DVT's in her lower extremities. (We had tried Coumadin first but even when therapeutic, she still got a DVT.) She had tolerated Xarelto then, but had to stop due to some bleeding issues. She had an IVC filter placed at that time. Unfortunately, another DVT occurred a year later, so we tried Eliquis. After about 3 weeks she developed a rash on her legs which slowly started to creep up her entire body. I am a pharmacist and tried everything I could think of to control this itchy rash. Nothing worked- we tried every steroid cream, calamine lotion, every antihistamine, gabapentin, Alveeno baths. I took her to 5 dermatologist, even University of Chicago. Finally, the last dermatologist asked me if we had ever tried UVB Narrowbandlight therapy- BINGO!- that stopped the itching, the rash healed.
(He calls it hospice for the skin.) Find a dermatologist that offers this treatment, it works! We started going 3 times a week, then I was able to cut it down to twice a week, then once a week, then after about 1 year, I was able to stop treatments altogether. Just recently, she developed another DVT and her physician put her back on Xarelto. Now, I am seeing an itchy rash develop with the Xarelto. I am going to get her cardiologist to stop the Xarelto, switch to Lovenox to finish her therapy for now and go back to the UVB treatment (called lightbox by those who use it) UVB has been a life-saver! (No, sun tanning places can't be substituted for UVB, but many insurances will cover all or part of therapy) Ask about private paying. It is worth the cost! Mom can't stand in the "booth" anymore so I place a 5 gallon plastic bucket with a seat cover for her to sit on or you can use a small folding stool.) If this helps you, companies make portable units you can use at home, but get the rash under control first at the dermatologist office. The home units are expensive and mom's insurance would not cover a home unit. It is an inconvenience going 3 times a week at first (mom is only in the box for 1-2 minutes each treatment) but then try going less; you will get the hang of when you need to go and what frequency works for you. Good luck everyone- hope this helps!
I developed a rash on my arms and back of my neck after radiation treatments and a DVT put on Xarelto. My oncologist, radiologist and primary care doctors were stumped. My primary care doctor prescribed prednisone, starting with 6 a day, down to 1 pill. The rash disappeared. But after about a week, it came back. I am still on Xarelto, 20 mg once a day. Odds appear to me to be the Xarelto. I get some temporary relief with pure aloe, lanacaine and benadry gel . Any other skin lotions do not help. Good luck to all dealing with this.
I’m on Xarelto. My arms are full of red spots and blotches. They start to fade then come back. They don’t itch .I wear long sleeves when I go out, even in the hot weather. It’s embarrassing for me being a woman.
I am taking Eliquis after a heart ablation to treat Afib. I developed itching rash on my back that also has developed on my face. It subsided on the back on its own. The face was terrible but was treated with steroid ointment and cleared up after a few days. Face stayed clear a few weeks but has returned a little milder. I was going to ask Dr. to change medications but it sounds like the rash is a symptom for all of the blood thinners. Hopefully the ablation will eliminate the need for blood thinner but Dr. said as a female I will have to go back on blood thinners at age 75 anyway. Maybe the rashes will have been refined out in a few years.
A few years ago, this happened while on warfarin. Went away when I discontinued it. A few months ago, I had a dvt and am on xarelto this time. The itchy rash is back and I am quite discouraged after reading these comments. I have to take blood thinners for the rest of my life and am not happy that this is a problem with all of them, apparently.
My doctor has prescribed 4 different blood thinners Apixaban, Xarelto and Coumadin, the name of the other ı forget at the moment. ı have had allergic reactions to ALL of the above. The reaction is under the skin red blood filled spots on the lower leg which thankfully were not itchy but as treatment proceeded the extent of the rash increased even down to the feet. ı am now taking 100mg aspirin in the hope that this will stop any blood clotting. ı cannot be alone in this reaction to blood thinners, ı would suggest that many of the adverse reactions to these bright shiny new drugs are not necessarily reported and they should be.
I’ve been taking Xarelto for a month after a 14cm DVT AND Bi lateral submassive Oulmonary Embolisms.
Two days ago I broke out in welts on my hands, stomach, feet and ears. I ended up at the dr and then emergency. They said I was allergic to something but nothing has changed except I went from 30mg to 20mg of Xarelto. No one thinks it could be this as I didn’t have any reaction for a month.
Anyone else experience similar? The itch is driving me crazy. I’m on steroids but it’s not doing much.
Rivaroxaban itch and rash is stopped by Laratadine..I am using Rivaroxaban and come out in a rash in several parts of my body starting with itching first when I do not combine it with my other medication to help with high levels of Histamine in my body. Laratadine, an antihistamine, cheap to buy online stops the itching and any rash completely for me. I discovered this by pure chance by stopping the Laratadine for 1 week as antihistamine seems to increase my appetite..I hope this is helpful
Yes! I'm taking xarelto I went to the emergency room few days after Christmas for what felt like a Charlie horse in my left leg. It turned red and felt like it was going to explode. After testing the doctor told me I have a few blood clots in my leg. I was shocked I'm 39 years old. I have CHF. From my only pregnancy. I work up to 10 hrs a day but it's sitting. I know wear compression stockings due to my legs swelling from sitting. After around 2 months of being on xarelto I developed a rash on the top of my feet. It know goes up to my knees. It seems to be worse at night and that when I take my xarelto. It recently just started going further up much legs. Sometimes it will go away during the day and back again at night. Sometimes it's bumpy sometimes it's flat and it itches to where I'm scratching it in my sleep and it bleeds from that. I just told my husband two days ago it has to be from the xarelto.
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